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Official Description

Subtraction in conjunction with contrast studies

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 76350 refers to a specific imaging technique known as subtraction in conjunction with contrast studies. This procedure is utilized in radiology to enhance the visibility of certain structures or abnormalities within the body. In this context, subtraction involves the removal of images that do not contain contrast dye from a series of X-ray, CT (Computed Tomography), or MRI (Magnetic Resonance Imaging) images. The use of contrast agents is crucial as they help to highlight specific areas of interest, making it easier for physicians to identify and assess conditions such as tumors, vascular abnormalities, or other pathological changes. By eliminating non-contrast images, the resulting sequence provides a clearer and more focused view of the areas where the contrast has been applied, thereby improving diagnostic accuracy and aiding in clinical decision-making.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 76350 is indicated for various clinical scenarios where enhanced imaging is necessary to evaluate specific conditions. The following are the explicitly provided indications for performing this procedure:

  • Evaluation of Tumors This procedure is often utilized to assess the presence, size, and characteristics of tumors, allowing for better visualization of the tumor's relationship to surrounding tissues.
  • Assessment of Vascular Abnormalities Subtraction techniques are particularly useful in identifying vascular conditions, such as aneurysms or blockages, by providing a clearer view of blood vessels when contrast is used.
  • Detection of Inflammatory Processes The procedure can help in visualizing areas of inflammation or infection, as the contrast agent highlights affected tissues more distinctly.

2. Procedure

The procedure for CPT® Code 76350 involves several key steps that ensure the effective application of subtraction techniques in imaging studies. Each step is critical for achieving optimal results:

  • Step 1: Preparation of the Patient Prior to the imaging procedure, the patient is prepared by explaining the process and ensuring that they understand the use of contrast agents. Any contraindications to the use of contrast, such as allergies, are assessed and addressed.
  • Step 2: Administration of Contrast Agent A contrast agent is administered to the patient, typically through an intravenous line. This agent enhances the visibility of specific structures within the body during imaging.
  • Step 3: Image Acquisition The imaging sequence is performed using X-ray, CT, or MRI technology. Multiple images are captured, including those with and without the contrast agent, to provide a comprehensive dataset for analysis.
  • Step 4: Subtraction of Non-Contrast Images After the images are acquired, the non-contrast images are digitally subtracted from the contrast images. This process removes any background noise and highlights only the areas where the contrast agent is present, allowing for clearer visualization of the structures of interest.
  • Step 5: Review and Interpretation The resulting images are then reviewed by the physician or radiologist, who interprets the enhanced images to make diagnostic decisions based on the clearer representation of the anatomical structures.

3. Post-Procedure

After the completion of the subtraction imaging procedure, patients may be monitored for any immediate reactions to the contrast agent, particularly if it was administered intravenously. It is important to ensure that the patient is stable and does not exhibit any adverse effects. Patients are typically advised to hydrate adequately to help flush the contrast agent from their system. Follow-up instructions may include scheduling additional imaging or consultations based on the findings from the subtraction images. The physician will discuss the results with the patient and outline any further steps required for diagnosis or treatment.

Short Descr SPECIAL X-RAY CONTRAST STUDY
Medium Descr SUBTRCJ CONJUNCT C+ STD
Long Descr Subtraction in conjunction with contrast studies
Status Code Carriers Price the Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 3 - Technical Component Only Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 02 - Procedure must be performed under the direct supervision of a physician.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
Type of Service (TOS) 4 - Diagnostic Radiology
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.
CCS Clinical Classification 226 - Other diagnostic radiology and related techniques
Date
Action
Notes
2011-01-01 Deleted Deleted
Pre-1990 Added Code added.
Code
Description
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