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Official Description

Myocardial perfusion imaging, tomographic (SPECT) (including attenuation correction, qualitative or quantitative wall motion, ejection fraction by first pass or gated technique, additional quantification, when performed); multiple studies, at rest and/or stress (exercise or pharmacologic) and/or redistribution and/or rest reinjection

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Myocardial perfusion imaging is a specialized nuclear medicine procedure designed to assess the functionality of the heart muscle and the blood flow to the heart. This imaging technique utilizes a radionuclide, commonly referred to as a tracer, which is injected into the patient's bloodstream through an intravenous line placed in a vein, typically in the hand or arm. The procedure begins with the placement of electrocardiogram (ECG) leads to monitor the heart's electrical activity, along with a blood pressure cuff on the arm to track hemodynamic changes during the study. The patient is positioned flat on a table within the procedure room, where the imaging can be conducted either at rest or under stress conditions. For stress testing, the patient may engage in physical exercise on a treadmill or stationary bike, or alternatively, a pharmacologic agent may be administered to simulate the effects of exercise on the heart. As the radionuclide circulates, it preferentially accumulates in healthy heart tissue, while ischemic areas—those with reduced blood flow—do not absorb the tracer. The imaging is performed using single photon emission computed tomography (SPECT), a technique that captures detailed images of the heart and surrounding vessels by rotating a scanner around the patient's body to acquire data from multiple angles. The evaluation of heart wall motion is a critical component of this procedure, as it helps determine the heart muscle's efficiency in pumping blood throughout the body. The ejection fraction, which quantifies the percentage of blood expelled from the heart with each contraction, is measured using either a first pass technique—where images are captured during the initial circulation of the radionuclide—or a gated technique, which involves taking a series of images between heartbeats. This gated approach utilizes electrical signals from the heart to produce high-resolution images that provide a clearer view of cardiac function. Additional imaging may be performed as necessary, and the physician will analyze the results, calculate the ejection fraction, and assess other functional parameters based on the distribution of the radionuclide. Finally, a comprehensive written report detailing the findings is generated for further review and clinical decision-making.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The myocardial perfusion imaging procedure is indicated for various clinical scenarios where assessment of heart function and blood flow is necessary. The following conditions may warrant this imaging study:

  • Evaluation of Coronary Artery Disease This procedure is often performed to assess the presence and severity of coronary artery disease, which can lead to ischemic heart conditions.
  • Assessment of Myocardial Ischemia It is utilized to evaluate areas of the heart that may not be receiving adequate blood flow, particularly during stress conditions.
  • Preoperative Assessment Myocardial perfusion imaging may be indicated prior to surgical procedures to evaluate cardiac risk and function.
  • Post-Myocardial Infarction Evaluation Following a heart attack, this imaging can help determine the extent of damage to the heart muscle and guide further treatment.
  • Monitoring of Cardiac Conditions It is also used to monitor patients with known cardiac conditions to assess changes in heart function over time.

2. Procedure

The myocardial perfusion imaging procedure involves several key steps to ensure accurate assessment of heart function and blood flow. The following procedural steps are typically followed:

  • Step 1: Patient Preparation The patient is prepared for the procedure by placing an intravenous line in a vein, usually in the hand or arm. ECG leads are attached to monitor the heart's electrical activity, and a blood pressure cuff is placed on the arm to monitor hemodynamic status during the study.
  • Step 2: Rest Imaging For the initial phase of the study, the patient lies flat on a table while images of the heart are obtained at rest. A radionuclide tracer is injected through the intravenous line, allowing it to circulate and localize in healthy heart tissue.
  • Step 3: Stress Testing If a stress study is indicated, the patient may either exercise on a treadmill or stationary bike, or receive a pharmacologic agent to simulate exercise. This step is crucial for evaluating the heart's response under stress conditions.
  • Step 4: Radionuclide Injection During the stress phase, a radionuclide is injected to visualize blood flow to the heart muscle. The tracer will highlight areas of the heart that are receiving adequate blood flow versus those that are ischemic.
  • Step 5: SPECT Imaging The SPECT scanner rotates around the patient's body to capture images of the heart from multiple angles. This imaging technique provides detailed information about the heart's structure and function.
  • Step 6: Image Analysis The physician evaluates the obtained images to assess heart wall motion and calculate the ejection fraction using either the first pass or gated technique. Additional images may be taken as needed to clarify findings.
  • Step 7: Reporting After analysis, the physician compiles a written report detailing the findings, including any abnormalities in blood flow or heart function, which will guide further clinical management.

3. Post-Procedure

After the myocardial perfusion imaging procedure, patients are typically monitored for a short period to ensure there are no immediate adverse reactions to the radionuclide or stress testing. Patients may resume normal activities unless otherwise instructed by their physician. The results of the imaging study are usually reviewed and discussed with the patient in a follow-up appointment, where the physician will explain the findings and any necessary next steps in management or treatment based on the results. It is important for patients to understand the significance of the findings and how they relate to their overall cardiac health.

Short Descr HT MUSCLE IMAGE SPECT MULT
Medium Descr MYOCARDIAL SPECT MULTIPLE STUDIES
Long Descr Myocardial perfusion imaging, tomographic (SPECT) (including attenuation correction, qualitative or quantitative wall motion, ejection fraction by first pass or gated technique, additional quantification, when performed); multiple studies, at rest and/or stress (exercise or pharmacologic) and/or redistribution and/or rest reinjection
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 1 - Diagnostic Tests for Radiology Services
Multiple Procedures (51) 6 - Special payment adjustment rules on the technical component (TC) of multiple diagnostic cardiovascular services apply...
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Not Discounted when Multiple
ASC Payment Indicator Radiology service paid separately when provided integral to a surgical procedure on ASC list; payment based on OPPS relative payment weight.
Type of Service (TOS) 4 - Diagnostic Radiology
Berenson-Eggers TOS (BETOS) I1E - Standard imaging - nuclear medicine
MUE 1
CCS Clinical Classification 209 - Radioisotope scan and function studies

This is a primary code that can be used with these additional add-on codes.

0742T Add-on Code MPFS Status: Carrier Priced APC N Absolute quantitation of myocardial blood flow (AQMBF), single-photon emission computed tomography (SPECT), with exercise or pharmacologic stress, and at rest, when performed (List separately in addition to code for primary procedure)
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
ME The order for this service adheres to appropriate use criteria in the clinical decision support mechanism consulted by the ordering professional
TC Technical component; under certain circumstances, a charge may be made for the technical component alone; under those circumstances the technical component charge is identified by adding modifier 'tc' to the usual procedure number; technical component charges are institutional charges and not billed separately by physicians; however, portable x-ray suppliers only bill for technical component and should utilize modifier tc; the charge data from portable x-ray suppliers will then be used to build customary and prevailing profiles
MG The order for this service does not have applicable appropriate use criteria in the qualified clinical decision support mechanism consulted by the ordering professional
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
MH Unknown if ordering professional consulted a clinical decision support mechanism for this service, related information was not provided to the furnishing professional or provider
GC This service has been performed in part by a resident under the direction of a teaching physician
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
MC Ordering professional is not required to consult a clinical decision support mechanism due to the significant hardship exception of electronic health record or clinical decision support mechanism vendor issues
MF The order for this service does not adhere to the appropriate use criteria in the clinical decision support mechanism consulted by the ordering professional
QQ Ordering professional consulted a qualified clinical decision support mechanism for this service and the related data was provided to the furnishing professional
GZ Item or service expected to be denied as not reasonable and necessary
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
GA Waiver of liability statement issued as required by payer policy, individual case
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
CR Catastrophe/disaster related
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
MA Ordering professional is not required to consult a clinical decision support mechanism due to service being rendered to a patient with a suspected or confirmed emergency medical condition
X2 Continuous/focused services: for reporting services by clinicians whose expertise is needed for the ongoing management of a chronic disease or a condition that needs to be managed and followed with no planned endpoint to the relationship; reporting clinician service examples include but are not limited to: a rheumatologist taking care of the patient's rheumatoid arthritis longitudinally but not providing general primary care services
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
ET Emergency services
GW Service not related to the hospice patient's terminal condition
MB Ordering professional is not required to consult a clinical decision support mechanism due to the significant hardship exception of insufficient internet access
X1 Continuous/broad services: for reporting services by clinicians, who provide the principal care for a patient, with no planned endpoint of the relationship; services in this category represent comprehensive care, dealing with the entire scope of patient problems, either directly or in a care coordination role; reporting clinician service examples include, but are not limited to: primary care, and clinicians providing comprehensive care to patients in addition to specialty care
25 Significant, separately identifiable evaluation and management service by the same physician or other qualified health care professional on the same day of the procedure or other service: it may be necessary to indicate that on the day a procedure or service identified by a cpt code was performed, the patient's condition required a significant, separately identifiable e/m service above and beyond the other service provided or beyond the usual preoperative and postoperative care associated with the procedure that was performed. a significant, separately identifiable e/m service is defined or substantiated by documentation that satisfies the relevant criteria for the respective e/m service to be reported (see evaluation and management services guidelines for instructions on determining level of e/m service). the e/m service may be prompted by the symptom or condition for which the procedure and/or service was provided. as such, different diagnoses are not required for reporting of the e/m services on the same date. this circumstance may be reported by adding modifier 25 to the appropriate level of e/m service. note: this modifier is not used to report an e/m service that resulted in a decision to perform surgery. see modifier 57 for significant, separately identifiable non-e/m services, see modifier 59.
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
56 Preoperative management only: when 1 physician or other qualified health care professional performed the preoperative care and evaluation and another performed the surgical procedure, the preoperative component may be identified by adding modifier 56 to the usual procedure number.
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
AM Physician, team member service
FS Split (or shared) evaluation and management visit
FY X-ray taken using computed radiography technology/cassette-based imaging
GF Non-physician (e.g. nurse practitioner (np), certified registered nurse anesthetist (crna), certified registered nurse (crn), clinical nurse specialist (cns), physician assistant (pa)) services in a critical access hospital
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GX Notice of liability issued, voluntary under payer policy
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
JW Drug amount discarded/not administered to any patient
JZ Zero drug amount discarded/not administered to any patient
KV Dmepos item subject to dmepos competitive bidding program that is furnished as part of a professional service
KX Requirements specified in the medical policy have been met
LT Left side (used to identify procedures performed on the left side of the body)
MD Ordering professional is not required to consult a clinical decision support mechanism due to the significant hardship exception of extreme and uncontrollable circumstances
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
PN Non-excepted service provided at an off-campus, outpatient, provider-based department of a hospital
PO Excepted service provided at an off-campus, outpatient, provider-based department of a hospital
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q3 Live kidney donor surgery and related services
Q5 Service furnished under a reciprocal billing arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
QJ Services/items provided to a prisoner or patient in state or local custody, however the state or local government, as applicable, meets the requirements in 42 cfr 411.4 (b)
RT Right side (used to identify procedures performed on the right side of the body)
SA Nurse practitioner rendering service in collaboration with a physician
ST Related to trauma or injury
U2 Medicaid level of care 2, as defined by each state
U6 Medicaid level of care 6, as defined by each state
X3 Episodic/broad services: for reporting services by clinicians who have broad responsibility for the comprehensive needs of the patient that is limited to a defined period and circumstance such as a hospitalization; reporting clinician service examples include but are not limited to the hospitalist's services rendered providing comprehensive and general care to a patient while admitted to the hospital
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
XP Separate practitioner, a service that is distinct because it was performed by a different practitioner
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
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2011-01-01 Changed Short description changed.
2010-01-01 Added -
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