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Official Description

Hepatic function panel
This panel must include the following:

  • Albumin (82040)
  • Bilirubin, total (82247)
  • Bilirubin, direct (82248)
  • Phosphatase, alkaline (84075)
  • Protein, total (84155)
  • Transferase, alanine amino (ALT) (SGPT) (84460)
  • Transferase, aspartate amino (AST) (SGOT) (84450)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The hepatic function panel, represented by CPT® Code 80076, is a comprehensive set of laboratory tests designed to assess the health and functionality of the liver. This panel is crucial for diagnosing various liver conditions, including both acute and chronic liver diseases, as well as inflammation and scarring of liver tissue. Additionally, it plays a significant role in monitoring liver function in patients undergoing treatment with certain medications that may impact liver health. The tests included in this panel provide valuable insights into the liver's ability to perform its essential functions, such as producing proteins, processing waste products, and metabolizing substances. The components of the hepatic function panel encompass several key tests: albumin, total bilirubin, direct bilirubin, alkaline phosphatase, total protein, alanine aminotransferase (ALT), and aspartate aminotransferase (AST). Each of these tests contributes to a comprehensive understanding of liver health, allowing healthcare providers to make informed decisions regarding diagnosis and treatment.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The hepatic function panel is indicated for a variety of clinical scenarios, particularly when there is a need to evaluate liver health and function. The following conditions and symptoms may warrant the use of this panel:

  • Diagnosis of Liver Disease - The panel is utilized to diagnose both acute and chronic liver diseases, providing essential information about liver function.
  • Monitoring Liver Function - It is important for monitoring hepatic function in patients who are taking medications that may affect the liver, ensuring that any potential liver damage is detected early.
  • Assessment of Liver Inflammation - The tests can help identify inflammation of the liver, which may be due to various causes, including infections or autoimmune conditions.
  • Evaluation of Liver Scarring - The panel aids in assessing liver scarring (fibrosis or cirrhosis), which can result from chronic liver disease.

2. Procedure

The procedure for obtaining a hepatic function panel involves several key steps that ensure accurate testing and results. The following steps outline the process:

  • Step 1: Patient Preparation - Prior to the blood draw, the patient may be instructed to fast for a certain period, although specific fasting requirements can vary based on the physician's orders.
  • Step 2: Venipuncture - A qualified healthcare professional performs a venipuncture to collect a blood sample. This is done using a sterile needle and collection tube, ensuring that the specimen is obtained in a manner that minimizes contamination.
  • Step 3: Specimen Handling - The collected blood specimen is then properly labeled and transported to the laboratory for analysis. It is crucial that the specimen is handled according to laboratory protocols to maintain its integrity.
  • Step 4: Laboratory Testing - In the laboratory, serum or plasma from the blood sample is tested using quantitative enzymatic methods or quantitative spectrophotometry to measure the levels of the various components included in the hepatic function panel.
  • Step 5: Result Interpretation - Once the tests are completed, the results are compiled and interpreted by a qualified healthcare professional, who will assess the liver function based on the levels of albumin, bilirubin, alkaline phosphatase, total protein, ALT, and AST.

3. Post-Procedure

After the procedure, patients may experience minimal discomfort at the venipuncture site, which typically resolves quickly. There are generally no specific post-procedure care instructions required for patients following a hepatic function panel, as the blood draw is a routine procedure. However, patients should be advised to report any unusual symptoms or prolonged discomfort at the site of the blood draw. The results of the hepatic function panel will be reviewed by the healthcare provider, who will discuss the findings with the patient and determine if any further action or follow-up testing is necessary based on the results.

Short Descr HEPATIC FUNCTION PANEL
Medium Descr HEPATIC FUNCTION PANEL
Long Descr Hepatic function panel This panel must include the following: Albumin (82040) Bilirubin, total (82247) Bilirubin, direct (82248) Phosphatase, alkaline (84075) Protein, total (84155) Transferase, alanine amino (ALT) (SGPT) (84460) Transferase, aspartate amino (AST) (SGOT) (84450)
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1B - Lab tests - automated general profiles
MUE 1
CCS Clinical Classification 235 - Other Laboratory
GA Waiver of liability statement issued as required by payer policy, individual case
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GW Service not related to the hospice patient's terminal condition
Q4 Service for ordering/referring physician qualifies as a service exemption
AY Item or service furnished to an esrd patient that is not for the treatment of esrd
GZ Item or service expected to be denied as not reasonable and necessary
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
25 Significant, separately identifiable evaluation and management service by the same physician or other qualified health care professional on the same day of the procedure or other service: it may be necessary to indicate that on the day a procedure or service identified by a cpt code was performed, the patient's condition required a significant, separately identifiable e/m service above and beyond the other service provided or beyond the usual preoperative and postoperative care associated with the procedure that was performed. a significant, separately identifiable e/m service is defined or substantiated by documentation that satisfies the relevant criteria for the respective e/m service to be reported (see evaluation and management services guidelines for instructions on determining level of e/m service). the e/m service may be prompted by the symptom or condition for which the procedure and/or service was provided. as such, different diagnoses are not required for reporting of the e/m services on the same date. this circumstance may be reported by adding modifier 25 to the appropriate level of e/m service. note: this modifier is not used to report an e/m service that resulted in a decision to perform surgery. see modifier 57 for significant, separately identifiable non-e/m services, see modifier 59.
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
93 Synchronous telemedicine service rendered via telephone or other real-time interactive audio-only telecommunications system : synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located away at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that is sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction.
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CG Policy criteria applied
CR Catastrophe/disaster related
GC This service has been performed in part by a resident under the direction of a teaching physician
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
QW Clia waived test
SA Nurse practitioner rendering service in collaboration with a physician
TR School-based individualized education program (iep) services provided outside the public school district responsible for the student
U6 Medicaid level of care 6, as defined by each state
X2 Continuous/focused services: for reporting services by clinicians whose expertise is needed for the ongoing management of a chronic disease or a condition that needs to be managed and followed with no planned endpoint to the relationship; reporting clinician service examples include but are not limited to: a rheumatologist taking care of the patient's rheumatoid arthritis longitudinally but not providing general primary care services
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
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Action
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2013-01-01 Changed Description Changed
2009-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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