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Official Description

Methemalbumin

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83857 refers to a laboratory test that measures the levels of methemalbumin in the blood. Methemalbumin is an abnormal complex formed when albumin, a protein that helps maintain blood volume and pressure, binds with heme, a component of hemoglobin. This complex is typically associated with certain blood disorders, particularly hemolytic and hemorrhagic conditions, where there is destruction of red blood cells or significant bleeding. The presence of methemalbumin can impart a distinctive brown color to the plasma, which is a key indicator of these underlying disorders. To perform this test, a blood sample is collected through a procedure known as venipuncture, which is separately reportable. The analysis of the serum or plasma is conducted using a technique called spectrophotometry, which measures the amount of light absorbed by the sample at specific wavelengths, allowing for the quantification of methemalbumin levels in the blood.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The methemalbumin test is indicated for the evaluation of patients suspected of having hemolytic or hemorrhagic blood disorders. These conditions may present with symptoms such as unexplained anemia, jaundice, or signs of significant blood loss. The test helps in diagnosing the underlying cause of these symptoms by detecting the presence of methemalbumin in the blood.

  • Hemolytic Disorders Conditions where red blood cells are destroyed faster than they can be produced, leading to anemia and other complications.
  • Hemorrhagic Disorders Situations involving significant blood loss, which may result from trauma, surgery, or other medical conditions.

2. Procedure

The procedure for measuring methemalbumin levels involves several key steps that ensure accurate results. First, a qualified healthcare professional performs venipuncture to obtain a blood sample from the patient. This step is crucial as it allows for the collection of serum or plasma, which is necessary for the subsequent analysis. The blood sample is then processed in a laboratory setting. Once the sample is prepared, it undergoes testing using spectrophotometry. This analytical method involves passing light through the serum or plasma and measuring the amount of light absorbed at specific wavelengths. The degree of absorption correlates with the concentration of methemalbumin present in the sample, allowing for precise quantification of its levels.

  • Step 1: Venipuncture A healthcare professional performs venipuncture to collect a blood sample from the patient, ensuring proper technique to minimize discomfort and complications.
  • Step 2: Sample Preparation The collected blood sample is processed in the laboratory to separate the serum or plasma, which is required for the analysis.
  • Step 3: Spectrophotometric Analysis The prepared serum or plasma is subjected to spectrophotometry, where light is passed through the sample, and the absorption is measured to determine the methemalbumin concentration.

3. Post-Procedure

After the methemalbumin test is completed, the patient may experience minimal discomfort at the venipuncture site, which typically resolves quickly. There are no specific post-procedure care instructions required for this test, but patients should be monitored for any unusual reactions. The results of the test will be analyzed and reported by the laboratory, and the healthcare provider will discuss the findings with the patient to determine any necessary follow-up actions or treatments based on the results.

Short Descr ASSAY OF METHEMALBUMIN
Medium Descr METHEMALBUMIN
Long Descr Methemalbumin
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
Date
Action
Notes
Pre-1990 Added Code added.
Code
Description
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