© Copyright 2025 American Medical Association. All rights reserved.
The CPT® Code 85410 refers to a laboratory test that specifically measures the activity of alpha-2-antiplasmin, a crucial serine protease inhibitor in the human body. Alpha-2-antiplasmin plays a significant role in the regulation of fibrinolysis, which is the process of breaking down fibrin clots in the blood. By inactivating plasmin, the enzyme responsible for degrading fibrin and other plasma proteins, alpha-2-antiplasmin helps maintain hemostasis and prevent excessive bleeding. This test is particularly important in clinical settings for diagnosing conditions such as congenital alpha-2-plasmin inhibitor deficiency, which can lead to abnormal bleeding tendencies. Additionally, it is utilized to assess patients suffering from disseminated intravascular coagulation (DIC), a serious condition characterized by widespread clotting and bleeding, as well as in cases of fibrinolysis and liver disease, where the regulation of clotting factors may be compromised. Furthermore, the test is instrumental in monitoring the effects of fibrinolytic or antifibrinolytic therapies, ensuring that treatment is effective and that patients are not at risk of complications related to abnormal clotting. The procedure involves obtaining a blood sample through venipuncture, which is separately reportable, and testing the platelet-poor plasma using a chromogenic assay to accurately measure the activity of alpha-2-antiplasmin.
© Copyright 2025 Coding Ahead. All rights reserved.
The test coded as CPT® 85410 is indicated for several clinical scenarios where the measurement of alpha-2-antiplasmin activity is essential for diagnosis and management. The following conditions warrant the performance of this laboratory test:
The procedure for performing the test associated with CPT® 85410 involves several key steps to ensure accurate measurement of alpha-2-antiplasmin activity. The first step is the collection of a blood sample from the patient, which is typically obtained through a venipuncture. This procedure involves inserting a needle into a vein, usually in the arm, to draw blood. It is important to ensure that the blood sample is collected in a manner that minimizes contamination and preserves the integrity of the sample for testing.
After the procedure, the patient may experience minor discomfort at the venipuncture site, which typically resolves quickly. There are no specific post-procedure care instructions related to the alpha-2-antiplasmin test itself, but it is advisable for patients to keep the site clean and dry. The results of the test will be analyzed and reported to the healthcare provider, who will interpret the findings in the context of the patient's clinical condition. Depending on the results, further diagnostic testing or therapeutic interventions may be necessary to address any identified issues related to coagulation and fibrinolysis.
| Short Descr | FIBRINOLYTIC ANTIPLASMIN | Medium Descr | FBRNLYC FACTORS&INHIBITORS ALPHA-2 ANTIPLASMIN | Long Descr | Fibrinolytic factors and inhibitors; alpha-2 antiplasmin | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
| 90 | Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number. | 91 | Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient. |
|
Date
|
Action
|
Notes
|
|---|---|---|
| Pre-1990 | Added | Code added. |
Get instant expert-level medical coding assistance.