CPT® Code 88148

1. Indications

The procedure is indicated for the following conditions:

• Cervical Dysplasia - A condition characterized by abnormal cell growth on the surface of the cervix, which can be a precursor to cervical cancer.
• In Situ Carcinoma - A type of cancer that is confined to the site of origin and has not invaded surrounding tissues, often detected through cytopathology screening.
• Routine Screening - Recommended for women as part of regular health check-ups to monitor cervical health and detect any early signs of disease.

2. Procedure

The procedure involves several key steps that ensure accurate screening and evaluation of cervical or vaginal specimens:

• Specimen Collection - Cells are collected from the endocervix using a specialized tool, such as a brush or stick, to ensure an adequate sample is obtained for analysis.
• Slide Preparation - The collected specimen is then placed on a glass slide, prepared appropriately, and coverslipped to preserve the sample for examination.
• Automated Screening - An automated system, equipped with a microscope, full-color camera, and high-speed image-processing computer, screens the prepared slides for any abnormalities. This system identifies and marks abnormal cells or clusters, storing the images for further review.
• Manual Rescreening - Following the automated screening, a technician manually rescreens the entire slide under the supervision of a physician (pathologist). This step involves a complete reassessment to confirm or refute the automated findings.
• Communication of Findings - The results of the screening, including any identified abnormalities, are communicated to the treating physician. If abnormalities are detected, the pathologist may recommend further diagnostic procedures or a follow-up PAP smear at a shorter interval.

3. Post-Procedure

After the procedure, the patient may be advised on follow-up care based on the results of the cytopathology examination. If abnormal findings are reported, the physician may recommend additional tests such as colposcopy, endocervical curettage, or biopsy to further investigate the nature of the abnormalities. Patients may also be scheduled for another PAP smear sooner than the standard interval to monitor any changes in cervical health. It is essential for patients to discuss the results and any recommended follow-up actions with their healthcare provider to ensure appropriate management and care.