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Official Description

Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); additional sequential infusion of a new drug/substance, up to 1 hour (List separately in addition to code for primary procedure)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

An intravenous infusion is a medical procedure in which a specified substance or drug is delivered directly into a patient's bloodstream through a vein, typically in the arm. This method is utilized for various purposes, including therapy, prophylaxis, or diagnosis. During the procedure, a healthcare professional places an intravenous (IV) line into the patient's vein, allowing for the controlled administration of the substance or drug. The physician overseeing the infusion provides direct supervision, ensuring they are immediately available to address any complications that may arise during the process. Additionally, the physician conducts periodic assessments of the patient's condition and documents their response to the treatment being administered. This code, CPT® 96367, specifically refers to an additional sequential infusion of a new drug or substance for a duration of up to one hour, and it is used in conjunction with other infusion codes to accurately represent the services provided. It is important to note that this code is an add-on code, meaning it is billed in addition to the primary procedure code for the initial infusion.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The intravenous infusion procedure, as described by CPT® code 96367, is indicated for various clinical scenarios where the administration of a specific substance or drug is necessary. The following are the explicitly provided indications for this procedure:

  • Therapy Administration of medications or substances to treat a specific medical condition or disease.
  • Prophylaxis Use of substances or drugs to prevent the onset of a disease or condition.
  • Diagnosis Infusion of diagnostic agents to assist in the evaluation of a patient's medical condition.

2. Procedure

The procedure for administering an intravenous infusion using CPT® code 96367 involves several key steps, which are detailed below:

  • Step 1: Preparation The healthcare provider prepares the necessary equipment, including the intravenous (IV) line, the specified substance or drug, and any additional supplies required for the infusion. This preparation ensures that all materials are sterile and ready for use.
  • Step 2: Insertion of IV Line The provider selects an appropriate vein, typically in the patient's arm, and inserts the IV catheter. This step is crucial for establishing a direct route for the infusion of the drug or substance into the bloodstream.
  • Step 3: Administration of the Substance or Drug Once the IV line is in place, the specified substance or drug is administered through the IV. The infusion is monitored closely by the physician, who ensures that the correct dosage is delivered over the specified duration of up to one hour.
  • Step 4: Monitoring and Assessment Throughout the infusion, the physician conducts periodic assessments of the patient's vital signs and overall response to the treatment. This monitoring is essential to identify any potential adverse reactions or complications that may occur during the procedure.
  • Step 5: Documentation After the infusion is completed, the physician documents the procedure, including the substance or drug administered, the duration of the infusion, and the patient's response. This documentation is critical for medical records and billing purposes.

3. Post-Procedure

After the completion of the intravenous infusion using CPT® code 96367, the patient may require specific post-procedure care. This includes monitoring for any delayed reactions to the substance or drug administered. The healthcare provider should ensure that the IV site is clean and free from complications such as infection or phlebitis. Patients may be advised to report any unusual symptoms or side effects experienced after the infusion. Follow-up assessments may be scheduled to evaluate the effectiveness of the treatment and to determine if further infusions or additional therapies are necessary.

Short Descr TX/PROPH/DG ADDL SEQ IV INF
Medium Descr IV INFUSION THER PROPH ADDL SEQUENTIAL TO 1 HR
Long Descr Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); additional sequential infusion of a new drug/substance, up to 1 hour (List separately in addition to code for primary procedure)
Status Code Active Code
Global Days ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC) 5 - Incident To Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Not Discounted when Multiple
Berenson-Eggers TOS (BETOS) P6C - Minor procedures - other (Medicare fee schedule)
MUE 4
CCS Clinical Classification 231 - Other therapeutic procedures

This is an add-on code that must be used in conjunction with one of these primary codes.

96360 MPFS Status: Active Code APC S CPT Assistant Article 1Intravenous infusion, hydration; initial, 31 minutes to 1 hour
96365 MPFS Status: Active Code APC S CPT Assistant Article Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96374 MPFS Status: Active Code APC S CPT Assistant Article Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intravenous push, single or initial substance/drug
96409 MPFS Status: Active Code APC S Physician Quality Reporting PUB 100 CPT Assistant Article Chemotherapy administration; intravenous, push technique, single or initial substance/drug
96413 MPFS Status: Active Code APC S Physician Quality Reporting PUB 100 CPT Assistant Article Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96366 Addon Code MPFS Status: Active Code APC S CPT Assistant Article Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
X2 Continuous/focused services: for reporting services by clinicians whose expertise is needed for the ongoing management of a chronic disease or a condition that needs to be managed and followed with no planned endpoint to the relationship; reporting clinician service examples include but are not limited to: a rheumatologist taking care of the patient's rheumatoid arthritis longitudinally but not providing general primary care services
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
CR Catastrophe/disaster related
GW Service not related to the hospice patient's terminal condition
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
Q0 Investigational clinical service provided in a clinical research study that is in an approved clinical research study
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
Q5 Service furnished under a reciprocal billing arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
25 Significant, separately identifiable evaluation and management service by the same physician or other qualified health care professional on the same day of the procedure or other service: it may be necessary to indicate that on the day a procedure or service identified by a cpt code was performed, the patient's condition required a significant, separately identifiable e/m service above and beyond the other service provided or beyond the usual preoperative and postoperative care associated with the procedure that was performed. a significant, separately identifiable e/m service is defined or substantiated by documentation that satisfies the relevant criteria for the respective e/m service to be reported (see evaluation and management services guidelines for instructions on determining level of e/m service). the e/m service may be prompted by the symptom or condition for which the procedure and/or service was provided. as such, different diagnoses are not required for reporting of the e/m services on the same date. this circumstance may be reported by adding modifier 25 to the appropriate level of e/m service. note: this modifier is not used to report an e/m service that resulted in a decision to perform surgery. see modifier 57 for significant, separately identifiable non-e/m services, see modifier 59.
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
57 Decision for surgery: an evaluation and management service that resulted in the initial decision to perform the surgery may be identified by adding modifier 57 to the appropriate level of e/m service.
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
GA Waiver of liability statement issued as required by payer policy, individual case
GZ Item or service expected to be denied as not reasonable and necessary
JW Drug amount discarded/not administered to any patient
JZ Zero drug amount discarded/not administered to any patient
KX Requirements specified in the medical policy have been met
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
PO Excepted service provided at an off-campus, outpatient, provider-based department of a hospital
RT Right side (used to identify procedures performed on the right side of the body)
SA Nurse practitioner rendering service in collaboration with a physician
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2012-01-01 Changed Description Changed
2011-01-01 Changed Medium description changed.
2009-01-01 Added -
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