CPT® Code 0848T | Case2Code

Official Description

Digitization of glass microscope slides for in situ hybridization (eg, FISH), per specimen; initial single probe stain procedure (List separately in addition to code for primary procedure)

Common Language Description

The CPT® Code 0848T refers to the process of digitizing glass microscope slides specifically for in situ hybridization procedures, such as fluorescence in situ hybridization (FISH). This procedure involves converting traditional glass slides into a digital format, allowing for the captured images to be stored either on a local computer server or within a cloud-based archive. The digitization process enhances the ability to examine the slides remotely, enabling pathologists to analyze the images without the need for physical access to the slides. Additionally, this digital format facilitates the use of computer algorithms that can assist in providing pathologic diagnoses, offering a distinct advantage over traditional direct visualization through a microscope. The digitization process is particularly relevant for stained slides of tissue biopsy specimens, which are prepared and analyzed using in situ hybridization techniques to identify specific target RNA or DNA sequences. When reporting this procedure, it is important to note that CPT® Code 0848T should be used for the initial single probe stain procedure. For subsequent procedures, such as additional single probe stains or multiplex probe stains, different codes (0849T and 0850T, respectively) are designated for accurate billing and documentation. This structured approach to coding ensures that each aspect of the digitization and staining process is appropriately captured for reimbursement and record-keeping purposes.

1. Indications

The digitization of glass microscope slides for in situ hybridization is indicated for the following:

Pathologic Diagnosis This procedure is performed to facilitate the diagnosis of pathologic conditions by allowing for the identification of specific target RNA or DNA sequences within tissue specimens.
Remote Examination It enables pathologists to examine slides remotely, which is particularly useful in situations where physical access to the slides is limited or impractical.
Enhanced Analysis The digitization process supports the use of advanced computer algorithms that can assist in the interpretation of the slides, providing additional diagnostic insights beyond traditional microscopy.

2. Procedure

The procedure for digitization of glass microscope slides for in situ hybridization involves several key steps:

Preparation of the Slide Initially, a stained slide of a tissue biopsy specimen is prepared. This involves applying a specific staining technique to highlight the target RNA or DNA sequences that are to be analyzed.
Digitization Process Once the slide is prepared, it is then scanned using a specialized digital microscope or imaging system. This equipment captures high-resolution images of the slide, converting the physical specimen into a digital format.
Storage of Digital Images The captured images are subsequently stored on a local computer server or within a cloud-based archive. This storage solution allows for easy access and management of the digital images for future analysis.
Remote Access and Analysis After digitization, the images can be accessed remotely by pathologists or other healthcare professionals. This capability enables further examination and interpretation of the slides, utilizing both human expertise and computer algorithms to enhance diagnostic accuracy.

3. Post-Procedure

Post-procedure care for the digitization of glass microscope slides primarily involves ensuring that the digital images are securely stored and easily accessible for future use. It is essential to maintain the integrity of the digital files and ensure that they are backed up in a reliable manner. Additionally, pathologists may need to review the digital images for diagnostic purposes, which can be done remotely. There are no specific recovery considerations for the patient, as the procedure pertains to the digitization of slides rather than a direct intervention on the patient. However, ongoing monitoring of the digital storage system is recommended to ensure that the images remain available for future analysis and interpretation.

Short Descr	DGTZ GLS MCRSCP ISH 1ST
Medium Descr	DGTZ GLS MCRSCP SLD ISH 1ST SINGLE PROBE STAIN
Long Descr	Digitization of glass microscope slides for in situ hybridization (eg, FISH), per specimen; initial single probe stain procedure (List separately in addition to code for primary procedure)
Status Code	Carriers Price the Code
Global Days	ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC)	3 - Technical Component Only Code
Multiple Procedures (51)	0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50)	0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions	09 - Concept does not apply.
Assistant Surgeon (80, 82)	0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62)	0 - Co-surgeons not permitted for this procedure.
Team Surgery (66)	0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family	99 - Concept Does Not Apply
APC Status Indicator	Items and Services Packaged into APC Rates
Berenson-Eggers TOS (BETOS)	none
MUE	Not applicable/unspecified.