CPT® Code 0849T | Case2Code

Official Description

Digitization of glass microscope slides for in situ hybridization (eg, FISH), per specimen; each additional single probe stain procedure (List separately in addition to code for primary procedure)

Common Language Description

The CPT® Code 0849T refers to the process of digitizing glass microscope slides specifically for in situ hybridization procedures, such as fluorescence in situ hybridization (FISH). This procedure involves converting physical glass slides into a digital format, allowing for the captured images to be stored either on a local computer server or within a cloud-based archive. The digitization process enhances the ability to examine the slides remotely, enabling pathologists to analyze the images without being physically present in the laboratory. Additionally, this digital format facilitates the use of computer algorithms that can assist in providing pathologic diagnoses, which may offer advantages over traditional direct visualization through a microscope. In situ hybridization is a technique used to detect specific RNA or DNA sequences within tissue samples, and it often involves staining slides of tissue biopsy specimens. The digitization of these slides is crucial for further analysis and interpretation in an increasingly image-based medical environment. When performing this procedure, it is important to note that CPT® Code 0849T is used to report each additional single probe stain procedure, which should be listed separately in addition to the code for the primary procedure. For the initial single probe stain preparation, CPT® Code 0848T is reported, while CPT® Code 0850T is designated for each multiplex probe stain digitization.

1. Indications

The digitization of glass microscope slides for in situ hybridization is indicated for the following:

Pathologic Diagnosis This procedure is performed to facilitate the diagnosis of specific pathologic conditions by allowing for detailed examination of tissue samples.
Remote Analysis It enables pathologists to analyze slides remotely, which is particularly beneficial in situations where immediate access to the physical slides is not possible.
Enhanced Interpretation The digitized images can be further interpreted using advanced computer algorithms, improving diagnostic accuracy and efficiency.

2. Procedure

The procedure for digitization of glass microscope slides for in situ hybridization involves several key steps:

Preparation of the Slide A stained slide of a tissue biopsy specimen is prepared, which involves applying specific stains to the tissue to highlight the target RNA or DNA sequences for analysis.
Digitization Process The prepared glass microscope slide is then scanned using a specialized digital scanner. This scanner captures high-resolution images of the slide, converting the physical specimen into a digital format.
Storage of Digital Images The digitized images are stored on a local computer server or within a cloud-based archive, ensuring that they are easily accessible for future analysis and interpretation.
Remote Access and Analysis Once digitized, the images can be accessed remotely by pathologists or other healthcare professionals, allowing for collaborative diagnosis and review.
Application of Algorithms The digitized images may be analyzed using computer algorithms that assist in identifying specific pathologic features, enhancing the diagnostic process.

3. Post-Procedure

After the digitization procedure, the expected post-procedure care includes ensuring that the digital images are properly stored and backed up to prevent data loss. Pathologists may review the digitized slides at their convenience, and any findings should be documented in the patient's medical record. Additionally, the use of digital images may facilitate further consultations or second opinions, as the images can be easily shared with other specialists. There are no specific recovery considerations for the patient, as this procedure is performed on the slides rather than the patient directly.

Short Descr	DGTZ GLS MCRSCP ISH EA ADL 1
Medium Descr	DGTZ GLS MCRSCP SLD ISH EA ADDL 1 PROBE STAIN
Long Descr	Digitization of glass microscope slides for in situ hybridization (eg, FISH), per specimen; each additional single probe stain procedure (List separately in addition to code for primary procedure)
Status Code	Carriers Price the Code
Global Days	ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC)	3 - Technical Component Only Code
Multiple Procedures (51)	0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50)	0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions	09 - Concept does not apply.
Assistant Surgeon (80, 82)	0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62)	0 - Co-surgeons not permitted for this procedure.
Team Surgery (66)	0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family	99 - Concept Does Not Apply
APC Status Indicator	Items and Services Packaged into APC Rates
Berenson-Eggers TOS (BETOS)	none
MUE	Not applicable/unspecified.

This is an add-on code that must be used in conjunction with one of these primary codes.

88364

Addon Code Resequenced Code MPFS Status: Active Code APC N In situ hybridization (eg, FISH), per specimen; each additional single probe stain procedure (List separately in addition to code for primary procedure)