Coding Ahead
CasePilot
Medical Coding Assistant
Case2Code
Search and Code Lookup Tool
RedactPHI
HIPAA-Compliant PHI Redaction
DetectICD10CM
ICD-10-CM Code Detection
Log in Register free account
1 code page views remaining. Guest accounts are limited to 1 page view. Register free account to get 5 more views.
Log in Register free account

Official Description

Heart transplant, with or without recipient cardiectomy

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 33945 refers to a heart transplant, which may include the removal of the recipient's diseased heart, known as cardiectomy. This complex surgical operation is typically performed through a median sternotomy, which involves making an incision along the breastbone to access the heart. During the procedure, cardiopulmonary bypass is established to take over the function of the heart and lungs, allowing the surgeon to operate on a still and bloodless field. In most cases, an orthotopic heart transplant is performed, where the majority of the recipient's heart is excised, while leaving parts of the atria intact. The surgical steps involve carefully opening the right atrium and making incisions to facilitate the connection of the donor heart to the recipient's remaining cardiac structures. This intricate process ensures that the donor heart is properly anastomosed to the recipient's atria and major vessels, allowing for effective blood circulation post-transplant. The procedure concludes with the patient being weaned off the cardiopulmonary bypass, placement of chest tubes, and closure of the chest incisions, marking the end of a critical and life-saving intervention.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The heart transplant procedure described by CPT® Code 33945 is indicated for patients with severe heart disease or heart failure that cannot be managed by other medical or surgical treatments. The following conditions may warrant this procedure:

  • End-stage heart failure Patients experiencing advanced heart failure symptoms that significantly impair their quality of life and are unresponsive to conventional therapies.
  • Severe coronary artery disease Patients with extensive coronary artery disease that leads to ischemic heart disease and is not amenable to revascularization procedures.
  • Cardiomyopathy Individuals diagnosed with dilated, hypertrophic, or restrictive cardiomyopathy that results in significant left ventricular dysfunction.
  • Congenital heart defects Patients with complex congenital heart defects that cannot be corrected through surgical repair.

2. Procedure

The heart transplant procedure involves several critical steps to ensure the successful replacement of the diseased heart with a donor heart. The following outlines the procedural steps:

  • Step 1: Median sternotomy The surgeon begins by making a vertical incision along the sternum to gain access to the thoracic cavity and expose the heart.
  • Step 2: Establishing cardiopulmonary bypass Cardiopulmonary bypass is initiated, diverting blood away from the heart and lungs, allowing the surgical team to operate on a bloodless field.
  • Step 3: Cardiectomy or orthotopic procedure The diseased heart may be removed entirely (cardiectomy) or, more commonly, an orthotopic procedure is performed where most of the heart is excised, leaving parts of the atria intact.
  • Step 4: Opening the right atrium The right atrium of the recipient heart is opened along the atrioventricular groove, extending the incision to the coronary sinus and the right atrial appendage.
  • Step 5: Dividing the aorta and pulmonary artery The aorta and main pulmonary artery are transected at the valve commissures to facilitate the connection of the donor heart.
  • Step 6: Incising the left atrium The roof of the left atrium is incised between the aorta and the superior vena cava, and the incisions are extended to the left atrial appendage.
  • Step 7: Connecting donor pulmonary veins The donor pulmonary veins are connected to form a left atrial cuff, which will be anastomosed to the recipient's atrial structures.
  • Step 8: Anastomosing the donor heart The donor heart is then anastomosed to the remaining portions of the recipient's right or both left and right atria, ensuring proper alignment and connection.
  • Step 9: Connecting major vessels The donor aorta and pulmonary arteries are connected to the recipient's aorta and pulmonary arteries, completing the vascular connections necessary for circulation.
  • Step 10: Weaning off cardiopulmonary bypass The patient is gradually weaned off the cardiopulmonary bypass, allowing the new heart to take over its function.
  • Step 11: Closing the chest Chest tubes are placed to drain any excess fluid, and the chest incisions are closed securely to complete the procedure.

3. Post-Procedure

After the heart transplant procedure, patients typically require close monitoring in an intensive care unit (ICU) setting. Post-operative care includes managing pain, monitoring for signs of rejection, and ensuring proper function of the new heart. Patients may also need to start immunosuppressive therapy to prevent organ rejection. Recovery involves a gradual return to normal activities, with follow-up appointments to assess heart function and overall health. The length of hospital stay can vary based on individual recovery, but patients are generally discharged with specific instructions regarding medication management, lifestyle modifications, and signs of complications to watch for.

Short Descr TRANSPLANTATION OF HEART
Medium Descr HEART TRANSPLANT W/WO RECIPIENT CARDIECTOMY
Long Descr Heart transplant, with or without recipient cardiectomy
Status Code Restricted Coverage
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 2 - Team surgeons permitted; pay by report.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Inpatient Procedures, not paid under OPPS
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P2F - Major procedure, cardiovascular-Other
MUE 1
CCS Clinical Classification 176 - Other organ transplantation

This is a primary code that can be used with these additional add-on codes.

33924 Addon Code MPFS Status: Active Code APC C CPT Assistant Article Ligation and takedown of a systemic-to-pulmonary artery shunt, performed in conjunction with a congenital heart procedure (List separately in addition to code for primary procedure)
33929 Addon Code MPFS Status: Carrier Priced APC C Removal of a total replacement heart system (artificial heart) for heart transplantation (List separately in addition to code for primary procedure)
34714 Addon Code MPFS Status: Active Code APC N ASC N1 Open femoral artery exposure with creation of conduit for delivery of endovascular prosthesis or for establishment of cardiopulmonary bypass, by groin incision, unilateral (List separately in addition to code for primary procedure)
34716 Addon Code MPFS Status: Active Code APC N ASC N1 Open axillary/subclavian artery exposure with creation of conduit for delivery of endovascular prosthesis or for establishment of cardiopulmonary bypass, by infraclavicular or supraclavicular incision, unilateral (List separately in addition to code for primary procedure)
34833 Addon Code Resequenced Code MPFS Status: Active Code APC C CPT Assistant Article Open iliac artery exposure with creation of conduit for delivery of endovascular prosthesis or for establishment of cardiopulmonary bypass, by abdominal or retroperitoneal incision, unilateral (List separately in addition to code for primary procedure)
62 Two surgeons: when 2 surgeons work together as primary surgeons performing distinct part(s) of a procedure, each surgeon should report his/her distinct operative work by adding modifier 62 to the procedure code and any associated add-on code(s) for that procedure as long as both surgeons continue to work together as primary surgeons. each surgeon should report the co-surgery once using the same procedure code. if additional procedure(s) (including add-on procedure(s) are performed during the same surgical session, separate code(s) may also be reported with modifier 62 added. note: if a co-surgeon acts as an assistant in the performance of additional procedure(s), other than those reported with the modifier 62, during the same surgical session, those services may be reported using separate procedure code(s) with modifier 80 or modifier 82 added, as appropriate.
GC This service has been performed in part by a resident under the direction of a teaching physician
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
AG Primary physician
CR Catastrophe/disaster related
GZ Item or service expected to be denied as not reasonable and necessary
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
Date
Action
Notes
Pre-1990 Added Code added.
Code
Description
Code
Description
Code
Description
Code
Description
Code
Description
CasePilot

Get instant expert-level medical coding assistance.

Ask about:
CPT Codes Guidelines Modifiers Crosswalks NCCI Edits Compliance Medicare Coverage
Example: "What is CPT code 99213?" or "Guidelines for E/M services"