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Official Description

Proton treatment delivery; complex

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 77525 refers to the delivery of complex proton treatment therapy, a specialized form of radiation therapy. In this procedure, a physician administers a proton beam specifically aimed at a tumor. Proton therapy is particularly advantageous for treating tumors that are situated deep within the body, as it allows for precise targeting of the tumor while minimizing exposure and potential damage to surrounding healthy tissues. This precision is achieved through the unique physical properties of protons, which can be controlled to release their energy directly at the tumor site. The treatment is typically delivered to one or more designated treatment areas, employing two or more ports for each area. This may involve the use of matching or patching fields and/or multiple isocenters, which are points around which the proton beams are directed. Additionally, custom blocks and compensators may be utilized to further enhance the accuracy and effectiveness of the treatment, ensuring that the proton beam conforms to the shape of the tumor and accounts for variations in patient anatomy.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure described by CPT® Code 77525 is indicated for the treatment of various types of tumors, particularly those that are located beneath significant amounts of healthy tissue. The following conditions may warrant the use of complex proton treatment delivery:

  • Deep-seated tumors Tumors that are situated deep within the body, where traditional radiation therapy may pose a higher risk of damaging surrounding healthy tissues.
  • Specific cancer types Certain cancers, such as pediatric tumors, brain tumors, and prostate cancer, may benefit from the precision of proton therapy.
  • Recurrent tumors Tumors that have recurred after previous treatments may be targeted effectively with proton therapy to minimize further damage to healthy tissue.

2. Procedure

The procedure for complex proton treatment delivery involves several critical steps to ensure effective targeting of the tumor while protecting surrounding healthy tissue. The following outlines the procedural steps:

  • Step 1: Patient Preparation The patient is positioned on the treatment table, and imaging studies may be performed to accurately locate the tumor. This positioning is crucial for ensuring that the proton beam is directed precisely at the tumor site.
  • Step 2: Treatment Planning A detailed treatment plan is developed, which includes determining the appropriate energy levels of the proton beam, the number of treatment areas, and the configuration of ports. This plan is tailored to the individual patient's anatomy and the specific characteristics of the tumor.
  • Step 3: Delivery of Proton Beam The physician administers the proton beam therapy, utilizing two or more ports per treatment area. The treatment may involve matching or patching fields and/or multiple isocenters to ensure comprehensive coverage of the tumor while minimizing exposure to healthy tissues.
  • Step 4: Use of Custom Blocks and Compensators During the treatment, custom blocks and compensators are employed to shape the proton beam according to the tumor's contours. This customization enhances the precision of the treatment, allowing for optimal targeting of the tumor.

3. Post-Procedure

After the completion of the proton treatment delivery, patients may be monitored for any immediate side effects or reactions to the therapy. Post-procedure care typically includes follow-up appointments to assess the effectiveness of the treatment and to monitor for any potential complications. Patients may also receive guidance on managing any side effects that may arise, as well as recommendations for ongoing care and support. The recovery process may vary depending on the individual patient's condition and the extent of the treatment received.

Short Descr PROTON TREATMENT COMPLEX
Medium Descr PROTON TX DELIVERY COMPLEX
Long Descr Proton treatment delivery; complex
Status Code Carriers Price the Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 3 - Technical Component Only Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Not Discounted when Multiple
ASC Payment Indicator Radiology service paid separately when provided integral to a surgical procedure on ASC list; payment based on OPPS relative payment weight.
Type of Service (TOS) 6 - Therapeutic Radiology
Berenson-Eggers TOS (BETOS) P7A - Oncology - radiation therapy
MUE 2
CCS Clinical Classification 211 - Therapeutic radiology
Q0 Investigational clinical service provided in a clinical research study that is in an approved clinical research study
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2011-01-01 Changed Short description changed.
2001-01-01 Added First appearance in code book in 2001.
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