Coding Ahead
CasePilot
Medical Coding Assistant
Case2Code
Search and Code Lookup Tool
RedactPHI
HIPAA-Compliant PHI Redaction
DetectICD10CM
ICD-10-CM Code Detection
Log in Register free account
1 code page views remaining. Guest accounts are limited to 1 page view. Register free account to get 5 more views.
Log in Register free account
CPT®
78190

CPT® Code 78190
Deleted

Official Description

Kinetics, study of platelet survival, with or without differential organ/tissue localization

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

A kinetic study of platelet survival, as described by CPT® Code 78190, is a specialized diagnostic procedure that evaluates the lifespan and distribution of platelets within the body. This study is particularly relevant for patients diagnosed with idiopathic thrombocytopenic purpura (ITP), a condition characterized by an abnormally low platelet count, which can lead to increased bleeding and bruising. The procedure may include differential organ or tissue localization, allowing healthcare providers to identify the specific sites where platelets are being destroyed. This information is crucial for determining the most effective treatment options for patients, especially those who have not responded to initial steroid therapies or have experienced a relapse. By pinpointing the location of platelet destruction, clinicians can better assess the potential benefits of surgical interventions, such as splenectomy, which may be indicated in certain cases. The process involves obtaining a blood sample, preparing it for analysis, and utilizing a radioisotope tracer to track platelet behavior over time, providing valuable insights into the patient's condition and guiding further management strategies.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The kinetic study of platelet survival is indicated for the following conditions:

  • Idiopathic Thrombocytopenic Purpura (ITP) This study is particularly useful for diagnosing and monitoring patients with ITP, especially those who have not responded to steroid treatment or have experienced a relapse.

2. Procedure

The procedure for conducting a kinetic study of platelet survival involves several detailed steps to ensure accurate results:

  • Step 1: Blood Sample Collection A blood sample is obtained from the patient through venipuncture or by drawing from a heplock or intravenous line. This initial step is crucial for establishing a baseline platelet count, which will be used for comparison throughout the study.
  • Step 2: Preparation of Platelet-Rich Plasma After the blood sample is collected, it is centrifuged to separate the components, resulting in the extraction of platelet-rich plasma. This plasma contains the platelets that will be further analyzed in the study.
  • Step 3: Tracer Addition and Incubation A radioisotope tracer, specifically 111-Indium Oxine, is added to the prepared platelets. The mixture is then incubated to allow the tracer to bind effectively to the platelets, which is essential for tracking their movement and survival.
  • Step 4: Injection of Tracer-Tagged Platelets Once the incubation is complete, the tracer-labeled platelets are injected back into the patient. This step marks the beginning of the monitoring phase, where the behavior of the platelets will be observed over time.
  • Step 5: Blood Draws at Intervals Blood samples are drawn at specific intervals—15 minutes, 30 minutes, 60 minutes, 120 minutes, and/or 240 minutes, and then daily for 1 to 4 days. These samples are critical for assessing the survival and distribution of the platelets within the patient's system.
  • Step 6: Serial Abdominal Imaging Concurrently, serial abdominal imaging is performed using large field gamma scintillation cameras. Imaging is conducted at 30 minutes, 2 hours, 4 hours, and daily for 5 days to visualize the localization of the platelets and identify any sites of destruction.
  • Step 7: Interpretation and Reporting After the imaging and blood sampling are completed, the physician interprets the scintigraphic images and compiles a written report detailing the findings. This report is essential for guiding further treatment decisions based on the study results.

3. Post-Procedure

Post-procedure care involves monitoring the patient for any immediate reactions to the tracer injection and ensuring that follow-up blood draws and imaging are conducted as scheduled. The physician will review the results of the platelet survival study and the imaging findings to determine the next steps in the patient's management plan. Patients may require additional consultations to discuss treatment options based on the outcomes of the study, particularly if surgical intervention is being considered.
Short Descr PLATELET SURVIVAL KINETICS
Medium Descr KINETICS PLATELET W/WO DIFFRNTL ORGAN/TIS LOCLZJ
Long Descr Kinetics, study of platelet survival, with or without differential organ/tissue localization
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 1 - Diagnostic Tests for Radiology Services
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Not Discounted when Multiple
Type of Service (TOS) 4 - Diagnostic Radiology
Berenson-Eggers TOS (BETOS) I1E - Standard imaging - nuclear medicine
MUE Not applicable/unspecified.
CCS Clinical Classification 210 - Other radioisotope scan
Date
Action
Notes
2017-12-31 Deleted Code deleted.
2011-01-01 Changed Short description changed.
1991-01-01 Added First appearance in code book in 1991.
Code
Description
Code
Description
Code
Description
CasePilot

Get instant expert-level medical coding assistance.

Ask about:
CPT Codes Guidelines Modifiers Crosswalks NCCI Edits Compliance Medicare Coverage
Example: "What is CPT code 99213?" or "Guidelines for E/M services"