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Chromatography is a sophisticated laboratory technique utilized for the separation of chemical components within a mixture. This process employs two distinct phases: a stationary phase and a mobile phase. In the context of column chromatography, the stationary phase is established by applying a thin layer of a liquid or polymer that contains the test sample onto a solid, inert support material. This support is then inserted into a column, which can be constructed from glass or metal, and is sealed to maintain the integrity of the sample during analysis. To enhance the efficiency of the separation process, the column may be subjected to controlled heating using an oven or similar device, which regulates the temperature throughout the procedure. The mobile phase, which can be either a gas or a liquid solvent, is introduced into the system, initiating the separation of the sample's components, known as analytes. The movement of these analytes through the column is influenced by their polarity, which determines the distance they travel in conjunction with the solvent. The CPT® Code 82491 is specifically designated for the quantitative analysis of a single analyte that is not specified elsewhere. This code is essential for accurately measuring the concentration of various substances within a sample, such as Coenzyme Q10, thiopurine metabolites, iodide, citalopram, strychnine, lipid peroxides (TBARS), cyclobenzaprine (Flexeril), buspirone (Buspar), pyridostigmine (Mestinon), bendiocarb, chloral hydrate, and phenazopyridine (Phenazo). In contrast, CPT® Code 82492 is utilized for the quantification of multiple analytes within a single sample, including substances like parathion, ketamine, and fractionated porphyrins.
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The procedure associated with CPT® Code 82491 is indicated for the quantitative analysis of specific chemical substances within a sample. This analysis is crucial for various clinical and research applications where precise measurement of a single analyte is required. The following conditions or scenarios may warrant the use of this procedure:
The procedure for CPT® Code 82491 involves several critical steps to ensure accurate quantification of the specified analyte. The process begins with the preparation of the sample, where a microscopic layer of the liquid or polymer containing the analyte is applied to a solid, inert support. This support is then placed into a column, which is typically made of glass or metal, and sealed to prevent contamination or loss of the sample. The column is often subjected to controlled heating, which helps to optimize the separation process by regulating the temperature of the mobile phase.
After the chromatography procedure is completed, the results are analyzed to determine the concentration of the single analyte in the sample. It is essential to document the findings accurately, as this data may be used for further clinical decision-making or research purposes. Depending on the specific analyte tested, additional follow-up may be required to interpret the results in the context of the patient's health or treatment plan. Proper storage and handling of the results are also crucial to maintain their integrity for future reference or audits.
Short Descr | CHROMOTOGRAPHY QUANT SING | Medium Descr | CHROMATOGRAPHY QUAN COLUMN 1 ANALYTE NES | Long Descr | Chromatography, quantitative, column (eg, gas liquid or HPLC); single analyte not elsewhere specified, single stationary and mobile phase | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | APC Status Indicator | Items and Services Packaged into APC Rates | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | Not applicable/unspecified. | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
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2016-01-01 | Deleted | Code deleted, to report see specific analyte code, or 82542 |
2011-01-01 | Changed | Short description changed. |
1993-01-01 | Added | First appearance in code book in 1993. |