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Official Description

Hepatitis B vaccine (HepB), dialysis or immunosuppressed patient dosage, 4 dose schedule, for intramuscular use

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 90747 refers to the Hepatitis B vaccine (HepB) specifically designed for patients who are undergoing dialysis or are immunosuppressed. This vaccine is administered in a 4-dose schedule via intramuscular injection. Unlike immune globulins, which offer short-term, passive immunity, vaccines like HepB provide active, long-term immunity. This is achieved by exposing the recipient's immune system to altered forms of the hepatitis B virus, prompting the immune system to produce its own antibodies. Consequently, the body retains the ability to generate these antibodies upon subsequent exposure to the virus, thereby offering protection against hepatitis B, a chronic and potentially serious liver disease that can lead to hospitalization and even death. The hepatitis B vaccine is significant not only for its role in preventing the disease but also for its potential to avert long-term complications such as hepatocellular carcinoma, making it one of the pioneering cancer vaccines in clinical use. The vaccine can be derived from the blood plasma of asymptomatic carriers or synthesized through recombinant technology, where a plasmid containing the hepatitis gene is inserted into common baker's yeast. This yeast is then lysed, and the components are purified for use. It is important to note that the code 90747 specifically reports the hepatitis B vaccine product for intramuscular use, while the actual injection procedure is reported separately. Other related codes include 90739 for adult dosage in a 2-dose or 4-dose schedule, 90740 for dialysis or immunosuppressed patients in a 3-dose schedule, 90743 for an adolescent 2-dose schedule, 90744 for pediatric/adolescent dosage in a 3-dose schedule, and 90746 for adult 3-dose schedule dosage.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The Hepatitis B vaccine (CPT® Code 90747) is indicated for patients who are undergoing dialysis or are immunosuppressed. These patients are at a higher risk for hepatitis B infection due to their compromised immune systems, making vaccination essential for their protection against this serious liver disease.

  • Dialysis Patients Patients undergoing dialysis are often immunocompromised, which increases their susceptibility to infections, including hepatitis B.
  • Immunosuppressed Patients Individuals with weakened immune systems due to conditions such as HIV/AIDS, cancer treatments, or organ transplants are at a greater risk for hepatitis B and benefit from vaccination.

2. Procedure

The administration of the Hepatitis B vaccine (CPT® Code 90747) follows a structured procedure to ensure effective immunization. The vaccine is delivered intramuscularly, typically in the deltoid muscle of the upper arm. The 4-dose schedule is designed to provide optimal immune response and long-term protection against hepatitis B. The first dose is administered, followed by subsequent doses at specified intervals to enhance the immune response. Each dose is carefully documented to maintain accurate records of the vaccination schedule, which is crucial for patient follow-up and compliance with immunization guidelines.

  • Step 1: Preparation Prior to administration, the vaccine is prepared according to manufacturer guidelines, ensuring that it is stored at the appropriate temperature and is not expired.
  • Step 2: Administration The vaccine is administered intramuscularly, typically in the deltoid muscle, using a sterile technique to prevent infection.
  • Step 3: Documentation Each dose is documented in the patient's medical record, including the date of administration, the vaccine lot number, and the site of injection.
  • Step 4: Follow-Up Patients are advised on the importance of completing the full 4-dose schedule and are scheduled for follow-up appointments to receive subsequent doses.

3. Post-Procedure

After the administration of the Hepatitis B vaccine, patients may experience mild side effects such as soreness at the injection site, low-grade fever, or fatigue. These effects are generally short-lived and resolve without intervention. It is important for healthcare providers to monitor patients for any adverse reactions and provide guidance on managing common side effects. Patients should also be informed about the importance of completing the full vaccination series to ensure adequate protection against hepatitis B. Follow-up appointments should be scheduled to administer the remaining doses as per the 4-dose schedule, and patients should be encouraged to report any unusual symptoms or concerns following vaccination.

Short Descr HEPB VACC 4 DOSE IMMUNSUP IM
Medium Descr HEPB VACCINE DIALYSIS/IMMUNSUP PAT 4 DOSE IM
Long Descr Hepatitis B vaccine (HepB), dialysis or immunosuppressed patient dosage, 4 dose schedule, for intramuscular use
Related Drugs ENGERIX-B
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Influenza, Pneumococcal Pneumonia, Hepatitis B, and Covid-19 Vaccines; Monoclonal Antibody Therapy Product
ASC Payment Indicator Corneal tissue acquisition, hepatitis B vaccine; paid at reasonable cost.
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) O1G - Immunizations/Vaccinations
MUE 1
CCS Clinical Classification 228 - Prophylactic vaccinations and inoculations
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
GC This service has been performed in part by a resident under the direction of a teaching physician
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
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Notes
2016-01-01 Changed First appearance of change in codebook.
2015-07-01 Changed Description Changed
2011-01-01 Changed Short description changed.
2001-01-01 Changed Code description changed.
1996-01-01 Added First appearance in code book in 1996.
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