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Official Description

Cardiopulmonary exercise testing, including measurements of minute ventilation, CO2 production, O2 uptake, and electrocardiographic recordings

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Cardiopulmonary exercise testing (CPET) is a sophisticated, noninvasive diagnostic procedure designed to assess the integrated response of the cardiovascular, pulmonary, and muscular systems during physical exertion. This test is particularly valuable for patients who present with symptoms such as shortness of breath, exercise intolerance, or chest pain/discomfort. By evaluating how well these systems function both independently and collectively during exercise, CPET can help identify the underlying causes of these symptoms. It is instrumental in diagnosing specific conditions, including heart failure, ischemic heart disease, valve dysfunction, pulmonary ventilation or circulation disorders, and muscular metabolic disorders. Furthermore, for patients with pre-existing medical conditions, CPET serves as a critical tool for monitoring disease progression and the effectiveness of therapeutic interventions. The testing is typically conducted on a stationary bicycle, allowing for controlled assessment of the patient's physical capabilities. Prior to initiating the exercise component of the test, baseline measurements such as spirometry and oximetry are obtained to establish reference values for lung function. During the test, various parameters are meticulously recorded, including minute ventilation, carbon dioxide production, oxygen uptake, and electrocardiographic data, providing a comprehensive overview of the patient's cardiopulmonary health. The results of the CPET are then analyzed by a physician, who interprets the findings and generates a detailed report, aiding in clinical decision-making and patient management.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

Cardiopulmonary exercise testing (CPET) is indicated for a variety of clinical scenarios where assessment of the cardiopulmonary system is necessary. The following conditions and symptoms warrant the performance of CPET:

  • Shortness of Breath: Patients experiencing unexplained dyspnea can benefit from CPET to determine the underlying cause.
  • Exercise Intolerance: Individuals who are unable to perform physical activities due to fatigue or discomfort may require CPET to evaluate their functional capacity.
  • Chest Pain/Discomfort: CPET can help differentiate between cardiac and non-cardiac causes of chest pain.
  • Heart Failure: For patients with known heart failure, CPET is useful in assessing functional status and response to treatment.
  • Ischemic Heart Disease: The test can identify exercise-induced ischemia, aiding in the diagnosis of coronary artery disease.
  • Valve Dysfunction: CPET can evaluate the impact of valvular heart disease on exercise capacity.
  • Pulmonary Disorders: Conditions affecting lung function, such as chronic obstructive pulmonary disease (COPD) or asthma, can be assessed through CPET.
  • Muscular Metabolic Disorders: The test can help diagnose and monitor conditions affecting muscle metabolism during exertion.

2. Procedure

The procedure for cardiopulmonary exercise testing (CPET) involves several key steps to ensure accurate and comprehensive assessment of the patient's cardiopulmonary function during exercise. The following outlines the procedural steps:

  • Step 1: Preliminary Testing Before the CPET begins, baseline spirometry and oximetry tests are conducted to establish reference values for lung function and oxygen saturation. These preliminary tests are crucial for comparing results obtained during the exercise phase.
  • Step 2: Equipment Setup The technician prepares the patient for the test by fitting them with necessary equipment, which includes a face mask for measuring ventilation, an electrocardiogram (EKG) to monitor heart activity, a blood pressure cuff for continuous blood pressure readings, and a pulse oximeter to assess oxygen levels in the blood.
  • Step 3: Warm-Up Phase The patient begins the exercise component by pedaling lightly on a stationary bicycle. This warm-up phase is essential for gradually acclimating the patient to the exercise conditions and ensuring their safety.
  • Step 4: Incremental Exercise Testing As the test progresses, the resistance against which the patient pedals is gradually increased, making the exercise more challenging. The patient continues to pedal until they reach maximum effort or experience significant symptoms that necessitate stopping the test. This phase is critical for evaluating the patient's exercise capacity and cardiopulmonary response.
  • Step 5: Monitoring Vital Signs Throughout the exercise, vital signs, including heart rate, blood pressure, and respiratory parameters, are continuously monitored to ensure patient safety and to collect data for analysis.
  • Step 6: Cool Down Phase After reaching maximum effort, the patient undergoes a gentle cool down, allowing their body to gradually return to a resting state. This phase is important for monitoring any post-exercise changes in vital signs and overall well-being.
  • Step 7: Post-Exercise Testing Following a brief rest period, a repeat lung function test is performed to assess any changes in lung capacity or function as a result of the exercise.

3. Post-Procedure

After the completion of the cardiopulmonary exercise testing (CPET), the patient is typically monitored for a short period to ensure they have fully recovered from the exercise. The physician will review the collected data, which includes measurements of minute ventilation, carbon dioxide production, oxygen uptake, and electrocardiographic recordings. A written interpretation of the findings is then provided, which may include insights into the patient's exercise capacity, any abnormalities detected during the test, and recommendations for further management or treatment based on the results. Patients may be advised on follow-up appointments to discuss the findings in detail and to plan any necessary interventions or lifestyle modifications.

Short Descr CARDIOPULM EXERCISE TESTING
Medium Descr CARDIOPULMONARY EXERCISE TESTING
Long Descr Cardiopulmonary exercise testing, including measurements of minute ventilation, CO2 production, O2 uptake, and electrocardiographic recordings
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 1 - Diagnostic Tests for Radiology Services
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Not Discounted when Multiple
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T2D - Other tests - other
MUE 1
CCS Clinical Classification 38 - Other diagnostic procedures on lung and bronchus
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
GC This service has been performed in part by a resident under the direction of a teaching physician
GZ Item or service expected to be denied as not reasonable and necessary
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
CR Catastrophe/disaster related
GA Waiver of liability statement issued as required by payer policy, individual case
GW Service not related to the hospice patient's terminal condition
KX Requirements specified in the medical policy have been met
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q5 Service furnished under a reciprocal billing arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
TC Technical component; under certain circumstances, a charge may be made for the technical component alone; under those circumstances the technical component charge is identified by adding modifier 'tc' to the usual procedure number; technical component charges are institutional charges and not billed separately by physicians; however, portable x-ray suppliers only bill for technical component and should utilize modifier tc; the charge data from portable x-ray suppliers will then be used to build customary and prevailing profiles
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XP Separate practitioner, a service that is distinct because it was performed by a different practitioner
Date
Action
Notes
2021-01-01 Note Guidelines changed.
2018-01-01 Changed Long medium and short descriptions changed.
1999-01-01 Added First appearance in code book in 1999.
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