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Official Description

Procalcitonin (PCT)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

A procalcitonin (PCT) test is a diagnostic procedure that measures the level of procalcitonin in the blood serum. Procalcitonin is a peptide that is produced by the body in response to bacterial infections, making it a highly specific biomarker for the early detection and therapeutic monitoring of clinically significant bacterial infections or sepsis. The presence of elevated procalcitonin levels in the bloodstream serves as an indicator not only of the existence of a bacterial infection but also of its severity. This test is particularly valuable in clinical settings as it aids healthcare providers in distinguishing between bacterial infections and viral infections or other forms of nonbacterial inflammation. The procedure involves obtaining a blood sample through a process known as venipuncture, which is separately reportable. The analysis of the blood sample is conducted using immunofluorescence techniques to accurately determine the serum concentrations of procalcitonin, thereby providing critical information for patient management and treatment decisions.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procalcitonin (PCT) test is indicated for the following conditions:

  • Bacterial Infection Detection The test is performed to identify the presence of clinically relevant bacterial infections.
  • Sepsis Monitoring It is utilized for the therapeutic monitoring of sepsis, helping to assess the severity of the condition.
  • Differentiation of Infection Types The test aids in differentiating between bacterial infections and viral infections or other nonbacterial inflammatory processes.

2. Procedure

The procedure for conducting a procalcitonin (PCT) test involves several key steps that ensure accurate measurement of procalcitonin levels in the blood serum.

  • Step 1: Patient Preparation Prior to the test, the patient may be instructed to follow specific guidelines, such as fasting or avoiding certain medications, to ensure the accuracy of the results.
  • Step 2: Venipuncture A qualified healthcare professional performs venipuncture to obtain a blood sample. This involves inserting a needle into a vein, typically in the arm, to draw a sufficient volume of blood for testing. The site is cleaned with an antiseptic to minimize the risk of infection.
  • Step 3: Sample Handling Once the blood sample is collected, it is properly labeled and handled according to laboratory protocols to prevent contamination and ensure integrity for analysis.
  • Step 4: Immunofluorescence Analysis The blood sample is then subjected to immunofluorescence techniques in the laboratory. This method allows for the precise measurement of procalcitonin concentrations in the serum, providing the necessary data for clinical interpretation.

3. Post-Procedure

After the procalcitonin (PCT) test is completed, the patient may experience minimal discomfort at the venipuncture site, which typically resolves quickly. There are generally no specific post-procedure care requirements, but patients should be advised to monitor the site for any signs of excessive bleeding or infection. The results of the test are usually available within a short timeframe, allowing for timely clinical decision-making regarding the diagnosis and management of bacterial infections or sepsis.

Short Descr PROCALCITONIN (PCT)
Medium Descr PROCALCITONIN (PCT)
Long Descr Procalcitonin (PCT)
APC Status Indicator Service Paid under Fee Schedule or Payment System other than OPPS
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.
CCS Clinical Classification 235 - Other Laboratory
Date
Action
Notes
2010-01-01 Deleted Code deleted effective 1/1/2010.
2009-01-01 Added -
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