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Official Description

Myocardial contrast perfusion echocardiography, at rest or with stress, for assessment of myocardial ischemia or viability (List separately in addition to code for primary procedure)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Myocardial contrast perfusion echocardiography (MCPE) is a specialized imaging procedure designed to evaluate the micro-perfusion of the heart muscle, either at rest or during stress conditions. This technique utilizes an intravenous infusion of microbubbles, which are tiny gas-filled spheres that mimic the behavior of red blood cells, allowing for enhanced visualization of blood flow within the myocardium. The microbubbles are composed of a hemodynamically inert gas core encased in a stabilizing outer shell, enabling them to traverse the pulmonary capillaries and enter systemic circulation. When subjected to high-intensity ultrasound (US), these microbubbles oscillate and can be destroyed, providing critical information about myocardial blood flow. MCPE is particularly useful in assessing myocardial ischemia, which occurs when there is insufficient blood flow to the heart muscle, and in evaluating myocardial viability, which refers to the heart muscle's ability to function after an ischemic event. The procedure can be performed in patients with acute myocardial infarction (AMI) to identify areas of heart muscle damage and to assess the effectiveness of therapeutic interventions. Additionally, MCPE can help delineate the extent of collateral perfusion and viable myocardium, which is essential for determining the prognosis and treatment strategies for patients with coronary artery disease (CAD). During the procedure, the patient is positioned supine on an examination table, and an intravenous line is established to facilitate the infusion of the microbubble solution. The ultrasound transducer is then placed on the chest to capture baseline images of myocardial function. Following the infusion of microbubbles, advanced imaging techniques and software are employed to measure parameters such as blood volume fraction and flow velocity, which are critical for determining myocardial blood flow. If indicated, stress testing may be conducted using a coronary vasodilator like dobutamine or through physical exertion on a reclining bicycle, allowing for a comprehensive comparison of myocardial function at rest and under stress conditions.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

Myocardial contrast perfusion echocardiography (MCPE) is indicated for the following conditions:

  • Assessment of Myocardial Ischemia - MCPE is utilized to evaluate areas of the heart muscle that may be experiencing insufficient blood flow, which is critical in diagnosing conditions such as coronary artery disease (CAD).
  • Evaluation of Myocardial Viability - The procedure helps determine the viability of heart muscle tissue, particularly in patients who have suffered an acute myocardial infarction (AMI), allowing for informed treatment decisions.
  • Assessment of Treatment Success - MCPE can be performed to assess the effectiveness of therapeutic interventions in patients with heart conditions, providing insights into the recovery of myocardial function.
  • Definition of Collateral Perfusion - The procedure aids in identifying the extent of collateral blood flow to the myocardium, which can be crucial for understanding the heart's adaptive mechanisms in response to ischemia.

2. Procedure

The procedure for myocardial contrast perfusion echocardiography (MCPE) involves several key steps that ensure accurate assessment of myocardial blood flow:

  • Patient Preparation - The patient is positioned supine on the examination table to facilitate optimal access to the chest for ultrasound imaging. An intravenous line is established to allow for the infusion of the microbubble solution.
  • Baseline Imaging - The ultrasound transducer is placed on the chest to capture baseline echocardiographic images of myocardial function. This initial imaging is crucial for establishing a reference point for subsequent assessments.
  • Infusion of Microbubbles - The infusion of the microbubble solution is initiated through the established intravenous line. The microbubbles, which behave like red blood cells, will enhance the ultrasound images by providing contrast that highlights blood flow within the myocardium.
  • Measurement of Myocardial Blood Flow - Advanced imaging techniques and specialized software are employed to measure parameters such as blood volume fraction and flow velocity. These measurements are essential for determining the rate of myocardial blood flow in the areas of interest.
  • Stress Testing - After capturing the information at rest, stress testing may be performed to further evaluate myocardial perfusion. This can be achieved through the administration of a coronary vasodilator, such as dobutamine, or by having the patient perform physical activity on a reclining bicycle. The end-systolic images acquired at rest and during stress are then compared side by side to assess any changes in myocardial perfusion.

3. Post-Procedure

Following the myocardial contrast perfusion echocardiography (MCPE), patients may be monitored for any immediate reactions to the microbubble infusion. It is important to assess the patient's overall condition and ensure that they are stable before discharge. The results of the MCPE will be analyzed and interpreted by a qualified healthcare professional, who will provide insights into myocardial ischemia and viability based on the imaging findings. Any necessary follow-up appointments or additional testing will be discussed with the patient to ensure comprehensive care and management of their cardiac health.

Short Descr MYOCRD CONTRAST PRFUJ ECHO
Medium Descr MYOCARDIAL PERFUSION ECHO ISCHM/VIABILITY ASSMT
Long Descr Myocardial contrast perfusion echocardiography, at rest or with stress, for assessment of myocardial ischemia or viability (List separately in addition to code for primary procedure)
Status Code Carriers Price the Code
Global Days ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
ASC Payment Indicator Packaged service/item; no separate payment made.
Berenson-Eggers TOS (BETOS) P5E - Ambulatory procedures - other
MUE 1

This is an add-on code that must be used in conjunction with one of these primary codes.

93306 MPFS Status: Active Code APC S CPT Assistant Article Echocardiography, transthoracic, real-time with image documentation (2D), includes M-mode recording, when performed, complete, with spectral Doppler echocardiography, and with color flow Doppler echocardiography
93307 MPFS Status: Active Code APC S PUB 100 CPT Assistant Article Echocardiography, transthoracic, real-time with image documentation (2D), includes M-mode recording, when performed, complete, without spectral or color Doppler echocardiography
93308 MPFS Status: Active Code APC S PUB 100 CPT Assistant Article Echocardiography, transthoracic, real-time with image documentation (2D), includes M-mode recording, when performed, follow-up or limited study
93350 MPFS Status: Active Code APC S PUB 100 CPT Assistant Article Echocardiography, transthoracic, real-time with image documentation (2D), includes M-mode recording, when performed, during rest and cardiovascular stress test using treadmill, bicycle exercise and/or pharmacologically induced stress, with interpretation and report;
93351 MPFS Status: Active Code APC S CPT Assistant Article Echocardiography, transthoracic, real-time with image documentation (2D), includes M-mode recording, when performed, during rest and cardiovascular stress test using treadmill, bicycle exercise and/or pharmacologically induced stress, with interpretation and report; including performance of continuous electrocardiographic monitoring, with supervision by a physician or other qualified health care professional
GZ Item or service expected to be denied as not reasonable and necessary
GC This service has been performed in part by a resident under the direction of a teaching physician
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
Date
Action
Notes
2017-01-01 Added First appearance in codebook.
2017-01-01 Changed Code description changed.
2016-07-01 Added Code added.
2016-01-01 Added Code Added
2016-01-01 Changed Change in AMA Guidelines
Code
Description
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