CPT® Code 0852T | Case2Code

Official Description

Digitization of glass microscope slides for morphometric analysis, in situ hybridization (quantitative or semiquantitative), manual, per specimen; each additional single probe stain procedure (List separately in addition to code for primary procedure)

Common Language Description

The CPT® Code 0852T refers to the process of digitizing glass microscope slides specifically for morphometric analysis and in situ hybridization, which can be either quantitative or semi-quantitative. This procedure involves converting physical glass slides into a digital format, allowing for the captured images to be stored on a local computer server or within a cloud-based archive. The digitization process facilitates further examination of the slides, enabling remote pathologists to analyze the images or utilizing computer algorithms to assist in providing a pathologic diagnosis, which is distinct from traditional direct visualization through a microscope. The information obtained from this digitization can be effectively managed and interpreted within an evolving image-based environment. The morphometric analysis that accompanies this procedure employs in situ hybridization techniques, which utilize fluorescent tagging to visualize specific genes or segments of genes. The manual preparation of glass slides, such as those derived from bone marrow or tumor samples, is performed for analysis, and the digitization of these slides occurs concurrently. It is important to note that for billing purposes, CPT® Code 0851T should be reported for the initial single probe stain preparation, while CPT® Code 0852T is designated for each additional single probe stain digitization. Additionally, CPT® Code 0853T is used for the digitization of each multiplex probe stain.

1. Indications

The procedure associated with CPT® Code 0852T is indicated for the following:

Digitization of Glass Microscope Slides This procedure is performed to convert glass microscope slides into a digital format for further analysis.
Morphometric Analysis It is utilized when morphometric analysis is required, allowing for quantitative or semi-quantitative assessment of cellular structures.
In Situ Hybridization The procedure is indicated for cases where in situ hybridization is necessary to visualize specific genes or gene segments within tissue samples.
Remote Pathology Review It is indicated when remote pathologists need to examine digitized images for diagnostic purposes.

2. Procedure

The procedure for CPT® Code 0852T involves several key steps:

Preparation of Glass Slides Initially, glass slides containing tissue samples, such as those from bone marrow or tumors, are prepared using manual techniques. This preparation is crucial for ensuring that the samples are suitable for analysis.
Digitization Process Once the slides are prepared, they undergo a digitization process where high-resolution images of the slides are captured. This process converts the physical slides into a digital format, allowing for storage on a local server or cloud-based archive.
Application of In Situ Hybridization Concurrently, in situ hybridization techniques are applied to the prepared slides. This involves using fluorescent tagging to visualize specific genes or portions of genes, which is essential for morphometric analysis.
Storage and Management of Digital Images After digitization, the images are stored and can be managed within an image-based environment, facilitating further analysis and interpretation by pathologists or through computer algorithms.

3. Post-Procedure

Post-procedure care for CPT® Code 0852T includes ensuring that the digitized images are securely stored and accessible for future analysis. Pathologists may review the images remotely, and the data obtained from the digitization can be utilized for further diagnostic purposes. It is essential to maintain the integrity of the digital files and ensure that they are backed up in a secure manner to prevent data loss. Additionally, any findings from the morphometric analysis and in situ hybridization should be documented thoroughly for compliance and future reference.

Short Descr	DGTZ GLS MCRSCP MPHMTRC EA 1
Medium Descr	DGTZ GLS MCRSCP SLD M/PHMTRC ISH EA ADD 1PRB STN
Long Descr	Digitization of glass microscope slides for morphometric analysis, in situ hybridization (quantitative or semiquantitative), manual, per specimen; each additional single probe stain procedure (List separately in addition to code for primary procedure)
Status Code	Carriers Price the Code
Global Days	ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC)	3 - Technical Component Only Code
Multiple Procedures (51)	0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50)	0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions	09 - Concept does not apply.
Assistant Surgeon (80, 82)	0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62)	0 - Co-surgeons not permitted for this procedure.
Team Surgery (66)	0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family	99 - Concept Does Not Apply
APC Status Indicator	Items and Services Packaged into APC Rates
Berenson-Eggers TOS (BETOS)	none
MUE	Not applicable/unspecified.

This is an add-on code that must be used in conjunction with one of these primary codes.

88369	Addon Code MPFS Status: Active Code APC N Morphometric analysis, in situ hybridization (quantitative or semi-quantitative), manual, per specimen; each additional single probe stain procedure (List separately in addition to code for primary procedure)
88369	Addon Code MPFS Status: Active Code APC N Morphometric analysis, in situ hybridization (quantitative or semi-quantitative), manual, per specimen; each additional single probe stain procedure (List separately in addition to code for primary procedure)