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A quadrivalent influenza virus vaccine, specifically identified by CPT® Code 90685, is a split virus formulation that is preservative-free and intended for intramuscular administration. This vaccine is designed to provide active, long-term immunity against influenza by introducing altered versions of the virus into the recipient's immune system. Unlike immune globulins, which offer short-term, passive immunity, vaccines stimulate the immune system to produce its own antibodies, enabling the body to recognize and combat the virus upon future exposure. The preservative-free aspect of this vaccine indicates that it does not contain the preservative thimerosal, or contains only trace amounts, and is classified as either thimerosal-free or thimerosal-reduced, both of which are recognized by the FDA as preservative-free. The vaccine is prepared using embryonated chicken eggs, where the virus is harvested, inactivated with formaldehyde, concentrated, purified, and chemically disrupted to create a split virus. This specific formulation protects against four strains of influenza viruses, including two type A strains and two type B strains. For accurate reporting, CPT® Code 90685 is used for a 0.25 mL dosage of the vaccine administered intramuscularly, while CPT® Code 90686 is designated for a 0.5 mL dosage. It is important to note that these codes solely represent the vaccine product and that the intramuscular injection itself should be reported separately.
© Copyright 2025 Coding Ahead. All rights reserved.
The quadrivalent influenza virus vaccine (IIV4) is indicated for the prevention of influenza caused by the four specific strains of the virus included in the vaccine formulation. The vaccine is recommended for individuals who are at risk of contracting influenza, particularly during the influenza season. The following conditions and populations may warrant vaccination:
The administration of the quadrivalent influenza virus vaccine involves several key procedural steps to ensure proper delivery and effectiveness of the vaccine:
Following the administration of the quadrivalent influenza virus vaccine, patients are typically advised to remain in the healthcare setting for a brief observation period to monitor for any immediate allergic reactions or side effects. Common post-vaccination reactions may include soreness at the injection site, mild fever, or fatigue, which usually resolve within a few days. Patients should be informed about the importance of reporting any severe or unusual reactions to their healthcare provider. Additionally, it is essential to remind patients that the vaccine does not provide immediate immunity and that it may take up to two weeks for the body to develop protective antibodies against the influenza virus. Regular follow-up and vaccination during the influenza season are recommended to maintain immunity.
Short Descr | IIV4 VACC NO PRSV 0.25 ML IM | Medium Descr | IIV4 VACC PRSRV FREE 0.25 ML DOS FOR IM USE | Long Descr | Influenza virus vaccine, quadrivalent (IIV4), split virus, preservative free, 0.25 mL dosage, for intramuscular use | Related Drugs | Afluria Quadrivalent | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | APC Status Indicator | Influenza, Pneumococcal Pneumonia, Hepatitis B, and Covid-19 Vaccines; Monoclonal Antibody Therapy Product | ASC Payment Indicator | Influenza vaccine; pneumococcal vaccine. | Type of Service (TOS) | V - Pneumococcal/Flu Vaccine | Berenson-Eggers TOS (BETOS) | O1G - Immunizations/Vaccinations | MUE | 1 | CCS Clinical Classification | 228 - Prophylactic vaccinations and inoculations |
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Notes
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2017-01-01 | Changed | Long, Medium and Short descriptions changed. |
2016-01-01 | Changed | First appearance of change in codebook. |
2015-07-01 | Changed | Description Changed |
2014-01-01 | Added | First appearance in codebook. |
2013-06-07 | Changed | Approved by FDA. Removed the 'Product Pending FDA Approval' flag. |
2013-01-01 | Added | Coded added |
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