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Official Description

Influenza virus vaccine, quadrivalent (ccIIV4), derived from cell cultures, subunit, antibiotic free, 0.5 mL dosage, for intramuscular use

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 90756 refers to the influenza virus vaccine, specifically a quadrivalent formulation that is derived from cell cultures. This vaccine is designed to provide active, long-term immunity against influenza by stimulating the recipient's immune system to produce antibodies. Unlike immune globulins, which offer short-term, passive immunity, vaccines like this one expose the immune system to altered versions of the influenza virus, prompting it to recognize and combat the actual virus upon future exposure. The quadrivalent aspect of this vaccine indicates that it is formulated to protect against four different strains of the influenza virus, which includes two strains of influenza type A and two strains of influenza type B. This particular vaccine is antibiotic-free and is produced in a sterile environment using cell cultures, ensuring that it does not contain any antibiotics. The dosage for this vaccine is 0.5 mL, and it is intended for intramuscular administration. It is important to note that this code specifically reports the product used, rather than any associated services or procedures.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The influenza virus vaccine, quadrivalent (ccIIV4), is indicated for the prevention of influenza disease caused by the four specific strains of the virus included in its formulation. The vaccine is recommended for individuals who are at risk of contracting influenza, particularly during the flu season. This includes, but is not limited to, the following populations:

  • High-Risk Individuals Individuals with chronic health conditions, such as asthma, diabetes, or heart disease, who may experience more severe complications from influenza.
  • Healthcare Workers Those who are in close contact with patients and may be at increased risk of exposure to the virus.
  • Children and Elderly Young children and older adults, who are generally more susceptible to influenza and its complications.
  • Pregnant Women Pregnant individuals, as they are at higher risk for severe illness from influenza.

2. Procedure

The administration of the quadrivalent influenza virus vaccine involves several key procedural steps to ensure safety and efficacy. First, the healthcare provider prepares the vaccine by ensuring that it is stored at the appropriate temperature and is not expired. The provider then selects the appropriate site for intramuscular injection, typically the deltoid muscle of the upper arm for adults and older children, or the anterolateral thigh for infants and young children. Prior to injection, the site is cleaned with an antiseptic wipe to minimize the risk of infection. The vaccine is then drawn into a syringe, and the provider ensures that there are no air bubbles present in the syringe. Following this, the needle is inserted into the muscle at a 90-degree angle, and the vaccine is injected slowly. After the injection, the provider may apply gentle pressure to the injection site with a cotton ball or gauze and may place a bandage over the area if necessary. Finally, the provider documents the administration of the vaccine in the patient's medical record, including the date, site of injection, and any relevant lot number information for tracking purposes.

3. Post-Procedure

After the administration of the quadrivalent influenza virus vaccine, patients are typically monitored for a short period to observe for any immediate adverse reactions, such as allergic responses. Common post-procedure care includes advising the patient to rest and hydrate adequately. Patients may experience mild side effects, such as soreness at the injection site, low-grade fever, or fatigue, which usually resolve within a few days. It is important for patients to be informed about these potential side effects and to seek medical attention if they experience any severe or unusual symptoms. Additionally, patients should be encouraged to follow up with their healthcare provider if they have any concerns regarding the vaccine or their health following administration.

Short Descr CCIIV4 VACC ABX FREE IM
Medium Descr CCIIV4 VACCINE ANTIBIOTIC FREE 0.5 ML DOS IM USE
Long Descr Influenza virus vaccine, quadrivalent (ccIIV4), derived from cell cultures, subunit, antibiotic free, 0.5 mL dosage, for intramuscular use
Related Drugs Flucelvax Quadrivalent
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Influenza, Pneumococcal Pneumonia, Hepatitis B, and Covid-19 Vaccines; Monoclonal Antibody Therapy Product
ASC Payment Indicator Influenza vaccine; pneumococcal vaccine.
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) none
MUE 1
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GA Waiver of liability statement issued as required by payer policy, individual case
GW Service not related to the hospice patient's terminal condition
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GC This service has been performed in part by a resident under the direction of a teaching physician
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
JZ Zero drug amount discarded/not administered to any patient
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
RT Right side (used to identify procedures performed on the right side of the body)
SA Nurse practitioner rendering service in collaboration with a physician
SL State supplied vaccine
U1 Medicaid level of care 1, as defined by each state
U6 Medicaid level of care 6, as defined by each state
X1 Continuous/broad services: for reporting services by clinicians, who provide the principal care for a patient, with no planned endpoint of the relationship; services in this category represent comprehensive care, dealing with the entire scope of patient problems, either directly or in a care coordination role; reporting clinician service examples include, but are not limited to: primary care, and clinicians providing comprehensive care to patients in addition to specialty care
X3 Episodic/broad services: for reporting services by clinicians who have broad responsibility for the comprehensive needs of the patient that is limited to a defined period and circumstance such as a hospitalization; reporting clinician service examples include but are not limited to the hospitalist's services rendered providing comprehensive and general care to a patient while admitted to the hospital
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2018-01-01 Added Code Added.
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Description
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