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Official Description

Influenza virus vaccine, quadrivalent (IIV4), split virus, 0.25 mL dosage, for intramuscular use

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 90687 refers to a specific type of influenza virus vaccine known as the quadrivalent influenza vaccine (IIV4). This vaccine is designed to provide protection against four different strains of the influenza virus, specifically two strains of influenza type A and two strains of influenza type B. The term "quadrivalent" indicates that the vaccine targets multiple strains, enhancing its effectiveness in preventing influenza infections during the flu season. The vaccine is classified as a split virus vaccine, meaning that the virus particles have been chemically disrupted to create a form that can stimulate an immune response without causing disease. This process involves the use of embryonated chicken eggs, where the virus is cultivated, harvested, and then inactivated using formaldehyde. The resulting vaccine is administered in a dosage of 0.25 mL via intramuscular injection. It is important to note that while vaccines like this one provide active, long-term immunity by prompting the immune system to produce antibodies, they differ from immune globulins, which offer short-term, passive immunity. When coding for this vaccine, it is essential to report the specific dosage administered, with code 90687 designated for the 0.25 mL dosage. Additionally, the intramuscular injection itself must be reported separately, as the CPT code only accounts for the vaccine product used.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The influenza virus vaccine, quadrivalent (IIV4), is indicated for the prevention of influenza disease caused by the four specific strains of the virus it targets. The vaccine is recommended for individuals who are at risk of contracting influenza, particularly during the flu season. The following conditions and populations may warrant the administration of this vaccine:

  • High-Risk Populations Individuals with chronic health conditions, such as asthma, diabetes, or heart disease, who are more susceptible to severe influenza complications.
  • Healthcare Workers Those who work in healthcare settings and are at increased risk of exposure to influenza viruses.
  • Older Adults Individuals aged 65 years and older, who may have a weakened immune response to infections.
  • Children Young children, particularly those aged 6 months to 5 years, who are at higher risk for hospitalization due to influenza.

2. Procedure

The administration of the quadrivalent influenza vaccine involves several key procedural steps to ensure proper delivery and effectiveness of the vaccine. The following steps outline the procedure:

  • Step 1: Preparation of the Vaccine The vaccine is prepared by ensuring that it is stored at the appropriate temperature and is not expired. The vial containing the vaccine is inspected for any particulate matter or discoloration before use.
  • Step 2: Patient Assessment Prior to administration, the healthcare provider assesses the patient’s medical history, including any previous allergic reactions to vaccines, current medications, and overall health status to determine eligibility for vaccination.
  • Step 3: Site Selection The healthcare provider selects an appropriate site for intramuscular injection, typically the deltoid muscle of the upper arm for adults and older children, or the anterolateral thigh for infants and young children.
  • Step 4: Injection Technique The vaccine is administered via intramuscular injection using a sterile syringe and needle. The needle is inserted at a 90-degree angle to the skin, and the vaccine is injected slowly to minimize discomfort.
  • Step 5: Post-Administration Care After the injection, the healthcare provider observes the patient for a brief period to monitor for any immediate adverse reactions. The patient is provided with information regarding potential side effects and the importance of reporting any unusual symptoms.

3. Post-Procedure

Post-procedure care for the administration of the quadrivalent influenza vaccine includes monitoring the patient for any immediate adverse reactions, such as allergic responses or injection site reactions. Patients are typically advised to rest and hydrate after receiving the vaccine. Common side effects may include soreness at the injection site, mild fever, or fatigue, which usually resolve within a few days. It is important for patients to be informed about the expected timeline for the development of immunity, which generally occurs about two weeks after vaccination. Additionally, patients should be encouraged to report any unusual or severe reactions to their healthcare provider. Follow-up appointments may be necessary for individuals requiring additional doses or for those who have specific health concerns.

Short Descr IIV4 VACCINE SPLT 0.25 ML IM
Medium Descr IIV4 VACC SPLIT VIRUS 0.25 ML DOS FOR IM USE
Long Descr Influenza virus vaccine, quadrivalent (IIV4), split virus, 0.25 mL dosage, for intramuscular use
Related Drugs Afluria Quadrivalent
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Influenza, Pneumococcal Pneumonia, Hepatitis B, and Covid-19 Vaccines; Monoclonal Antibody Therapy Product
ASC Payment Indicator Influenza vaccine; pneumococcal vaccine.
Type of Service (TOS) V - Pneumococcal/Flu Vaccine
Berenson-Eggers TOS (BETOS) O1G - Immunizations/Vaccinations
MUE 1
CCS Clinical Classification 228 - Prophylactic vaccinations and inoculations
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
GA Waiver of liability statement issued as required by payer policy, individual case
SL State supplied vaccine
Date
Action
Notes
2017-01-01 Changed Long, Medium and Short descriptions changed.
2016-01-01 Changed First appearance of change in codebook.
2015-07-01 Changed Description Changed
2014-01-01 Added First appearance in codebook.
2013-01-01 Added -
Code
Description
Code
Description
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