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Code deleted. For service dates in 2014, see 99481, 99482. For 2015 and beyond, use 99184

Official Description

Total body systemic hypothermia, per day, in the neonate 28 days of age or younger

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Total body systemic hypothermia is a medical procedure specifically designed for neonates who are 28 days of age or younger, particularly those diagnosed with hypoxic-ischemic encephalopathy (HIE). HIE is a serious condition that arises from a lack of adequate oxygen supply to the brain and spinal cord, often due to perinatal asphyxia. The procedure involves cooling the entire body or just the head of the neonate to a temperature range of 91.4°F (33°C) to 93.2°F (34°C). This cooling process is most effective when initiated within six hours following delivery, as it can significantly mitigate the neurological damage associated with HIE. The cooling is typically maintained for a duration of 72 hours, during which the infant's temperatures are meticulously monitored through various methods, including rectal, nasopharyngeal, scalp, and abdominal skin temperature assessments. Additionally, vital metabolic, cardiovascular, pulmonary, and coagulation laboratory measurements are conducted at predetermined intervals to ensure the neonate's safety and response to the treatment. Following the cooling phase, the procedure includes a gradual rewarming process that spans approximately four hours. For billing purposes, the CPT® Code 0260T is utilized to report each day of total body systemic hypothermia performed on eligible neonates.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure of total body systemic hypothermia is indicated for neonates who are 28 days of age or younger and are diagnosed with the following condition:

  • Hypoxic-Ischemic Encephalopathy (HIE) - A condition characterized by brain and spinal cord damage due to inadequate oxygen supply resulting from perinatal asphyxia.

2. Procedure

The procedure of total body systemic hypothermia involves several critical steps to ensure the safety and effectiveness of the treatment:

  • Step 1: Initiation of Hypothermia - The cooling process is initiated as soon as possible, ideally within six hours of the neonate's delivery. This prompt action is crucial for maximizing the therapeutic benefits of hypothermia in mitigating brain injury associated with HIE.
  • Step 2: Cooling Method - The entire body of the neonate, or in some cases just the head, is cooled using a specialized cooling blanket designed for this purpose. The target temperature range is maintained between 91.4°F (33°C) and 93.2°F (34°C) to ensure optimal therapeutic effects.
  • Step 3: Temperature Monitoring - Continuous monitoring of the neonate's temperature is performed through various methods, including rectal, nasopharyngeal, scalp, and abdominal skin temperature assessments. This monitoring is essential to ensure that the neonate remains within the desired temperature range throughout the procedure.
  • Step 4: Laboratory Assessments - During the cooling period, metabolic, cardiovascular, pulmonary, and coagulation laboratory measurements are conducted at predefined intervals. These assessments help in evaluating the neonate's physiological response to the hypothermia treatment and in identifying any potential complications.
  • Step 5: Duration of Cooling - The cooling is maintained for a total duration of 72 hours, during which the neonate is closely monitored for any changes in condition.
  • Step 6: Rewarming Phase - After the cooling period, the neonate undergoes a slow rewarming process that lasts approximately four hours. This gradual rewarming is critical to prevent any sudden physiological changes that could adversely affect the neonate's health.

3. Post-Procedure

Post-procedure care involves careful monitoring of the neonate as they transition from the hypothermic state back to normal body temperature. Healthcare providers will continue to assess the neonate's vital signs and overall condition during the rewarming phase. It is essential to observe for any signs of complications or adverse reactions that may arise as the body temperature normalizes. Additionally, ongoing evaluations of neurological function and other health parameters will be conducted to determine the effectiveness of the hypothermia treatment and to plan further care as needed.

Short Descr HYPTHRM BDY NEONATE 28D/
Medium Descr TOT BODY SYST HYPOTHER NEONATE AGE 28 DAYS/
Long Descr Total body systemic hypothermia, per day, in the neonate 28 days of age or younger
Status Code Carriers Price the Code
Global Days YYY - Carrier Determines Whether Global Concept Applies
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.
CCS Clinical Classification 231 - Other therapeutic procedures
Date
Action
Notes
2014-01-01 Deleted Code deleted. For service dates in 2014, see 99481, 99482. For 2015 and beyond, use 99184
2013-01-01 Changed Description Changed
2012-01-01 Added First appearance in code book.
2011-01-01 Added Released 2010-07-01. Implemented 2011-01-01.
Code
Description
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