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Code deleted, see 92499

Official Description

Quantitative pupillometry with interpretation and report, unilateral or bilateral

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Quantitative pupillometry is a sophisticated, noninvasive diagnostic technique that assesses the autonomic nervous system (ANS) by measuring the size and dynamic variability of the pupils. The procedure involves the evaluation of the iris, which contains two opposing muscle rings: the sphincter muscles and the dilator muscles. The sphincter muscles encircle the pupil and are responsible for constricting it to limit the amount of light entering the eye, primarily under the control of the parasympathetic nervous system. Conversely, the dilator muscles, which extend outward like bicycle spokes, facilitate pupil dilation in low-light conditions and are regulated by the sympathetic nervous system. During the pupillometry procedure, measurements can be taken unilaterally (in one eye) or bilaterally (in both eyes) using advanced technologies such as infrared illumination or LED stimulators. The changes in pupil size are captured through a camera, and the resulting images are transferred to a computer program for analysis. A physician or trained technician interprets the data and generates a comprehensive written report detailing the findings. Quantitative pupillometry serves a critical role in the diagnosis and management of various medical conditions, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, systemic sclerosis, omathropine-resistant non-cholinergic myosis, glaucoma, acute mountain sickness, hepatic encephalopathy, and congenital central hypoventilation syndrome. Additionally, it is utilized to assess and monitor patients experiencing severe head injuries or neurological deterioration due to intracranial issues, as well as to evaluate pain levels during anesthesia or medically induced coma.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

Quantitative pupillometry is indicated for a variety of conditions and symptoms that require assessment of the autonomic nervous system and pupil response. The following are the explicitly provided indications for this procedure:

  • Systemic Lupus Erythematosus - A chronic autoimmune disease that can affect multiple organ systems.
  • Sjogren's Syndrome - An autoimmune disorder characterized by dry eyes and dry mouth due to the destruction of glands that produce moisture.
  • Rheumatoid Arthritis - A chronic inflammatory disorder affecting joints, which may also have systemic effects.
  • Systemic Sclerosis - A group of autoimmune diseases that cause changes in the skin, blood vessels, muscles, and internal organs.
  • Omathropine-Resistant Non-Cholinergic Myosis - A condition where the pupil constricts abnormally and does not respond to typical treatments.
  • Glaucoma - A group of eye conditions that damage the optic nerve, often associated with increased intraocular pressure.
  • Acute Mountain Sickness - A condition that can occur when ascending to high altitudes too quickly, leading to various symptoms including headache and nausea.
  • Hepatic Encephalopathy - A decline in brain function as a result of severe liver disease.
  • Congenital Central Hypoventilation Syndrome - A disorder affecting the automatic control of breathing, particularly during sleep.
  • Severe Head Injury - To assess neurological function and potential damage following trauma.
  • Neurological Deterioration - Monitoring changes in neurological status due to intracranial pathology.
  • Pain Monitoring - To evaluate pain levels during anesthesia or medically induced coma.

2. Procedure

The procedure for quantitative pupillometry involves several key steps that ensure accurate measurement and analysis of pupil responses. The following procedural steps are outlined:

  • Step 1: Preparation - The patient is positioned comfortably in a controlled environment, ensuring minimal external light interference. The clinician explains the procedure to the patient to alleviate any anxiety and to obtain informed consent.
  • Step 2: Application of Stimulation - Depending on the specific requirements of the assessment, either infrared illumination or LED stimulators are used to induce changes in pupil size. This stimulation is crucial for evaluating the dynamic response of the pupils.
  • Step 3: Image Capture - A specialized camera is employed to capture real-time images of the pupils as they respond to the light stimuli. This step is essential for obtaining accurate data on pupil size and variability.
  • Step 4: Data Transfer - The captured images are downloaded to a computer program designed for analyzing pupillary responses. This software processes the images to quantify changes in pupil size over time.
  • Step 5: Interpretation - A qualified physician or technician reviews the analyzed data, interpreting the results in the context of the patient's clinical history and presenting symptoms. This interpretation is critical for understanding the implications of the findings.
  • Step 6: Reporting - A comprehensive written report is generated, summarizing the findings of the pupillometry assessment. This report includes detailed observations and interpretations that can guide further clinical decision-making.

3. Post-Procedure

After the quantitative pupillometry procedure, patients may be monitored briefly to ensure there are no immediate adverse reactions to the stimulation. Typically, there are no specific post-procedure care requirements, as the procedure is noninvasive and does not involve any recovery time. Patients can resume their normal activities immediately following the assessment. However, it is essential for the interpreting physician to discuss the findings with the patient, including any necessary follow-up actions or additional testing that may be warranted based on the results. Continuous monitoring may be recommended for patients with severe head injuries or neurological conditions to track any changes in their status over time.

Short Descr QUANT PUPILLOMETRY W/RPRT
Medium Descr QUANT PUPILLOMETRY W/INTERP&REPORT UNILAT/BILAT
Long Descr Quantitative pupillometry with interpretation and report, unilateral or bilateral
Status Code Carriers Price the Code
Global Days YYY - Carrier Determines Whether Global Concept Applies
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
Berenson-Eggers TOS (BETOS) P4E - Eye procedure - other
MUE Not applicable/unspecified.
Date
Action
Notes
2019-12-31 Deleted Code deleted, see 92499
2015-01-01 Added Added
2014-01-01 Added Added
Code
Description
Code
Description
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