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Code deleted, see 15275-15278

Official Description

Acellular dermal allograft, face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits; each additional 100 sq cm, or each additional 1% of body area of infants and children, or part thereof (List separately in addition to code for primary procedure)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

An acellular dermal allograft is a specialized medical procedure that involves the use of a skin graft derived from a cadaver donor, which has undergone chemical treatment to remove antigenic epidermal cellular components. This process minimizes the risk of immune rejection, making it a valuable option for covering skin defects or filling soft tissue defects in various anatomical areas, including the face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and multiple digits. Initially developed for treating burn victims, the application of acellular dermal allografts has expanded to include reconstructive surgery, dental and oral procedures, as well as plastic and cosmetic surgeries. The procedure entails the careful preparation of the graft, which is rehydrated in an isotonic sodium chloride solution and trimmed to fit the specific dimensions of the wound. The graft is then applied over the prepared wound bed, either in single or multiple layers, and secured with absorbable sutures. Any excess material is trimmed to ensure a proper fit. In cases where the graft is used to address a soft tissue defect, it may be covered with a separately reportable skin flap. Following the application of the graft, a layered dressing is placed, consisting of a bulky gauze layer, a compression layer, and an anti-shear layer to promote healing and protect the site. For billing purposes, CPT® Code 15335 is utilized for the first 100 square centimeters or less in adults or for 1% of total body surface area (TBSA) in infants and children, while CPT® Code 15336 is designated for each additional 100 square centimeters in adults or each additional 1% of TBSA in infants and children, or part thereof.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The acellular dermal allograft procedure is indicated for various conditions and situations where skin or soft tissue defects need to be addressed. These indications include:

  • Skin Defects The procedure is performed to cover skin defects resulting from trauma, surgical excisions, or congenital anomalies.
  • Soft Tissue Defects It is utilized to fill soft tissue defects that may arise from injury, disease, or surgical interventions.
  • Reconstructive Surgery The graft is often indicated in reconstructive surgeries aimed at restoring the appearance and function of affected areas.
  • Burn Treatment Initially developed for burn patients, the graft is indicated for treating burn wounds that require skin coverage.
  • Dental and Oral Procedures It is also indicated in dental and oral surgeries where soft tissue coverage is necessary.
  • Plastic and Cosmetic Procedures The graft is used in various plastic and cosmetic procedures to enhance aesthetic outcomes.

2. Procedure

The procedure for applying an acellular dermal allograft involves several critical steps to ensure proper placement and integration with the surrounding tissue. These steps include:

  • Preparation of the Graft The acellular dermal allograft is removed from its packaging and rehydrated in an isotonic sodium chloride solution. This step is essential to restore the graft's pliability and facilitate its application to the wound bed.
  • Trimming the Graft Once rehydrated, the graft is trimmed to the appropriate dimensions based on the size and shape of the wound. This ensures that the graft will adequately cover the defect without excess material that could impede healing.
  • Application of the Graft The trimmed graft is then applied over the prepared wound bed. Depending on the size of the defect, the graft may be placed in a single layer or multiple layers to achieve the desired coverage and support.
  • Securing the Graft The graft is secured in place using absorbable sutures, which help to hold the graft firmly against the wound bed while allowing for eventual absorption and healing.
  • Trimming Excess Material Any excess graft material at the periphery of the wound is trimmed to ensure a neat and effective fit, which is crucial for optimal healing.
  • Covering with Skin Flap (if applicable) If the acellular dermal allograft is being used to fill a soft tissue defect, it may be covered with a separately reportable skin flap to provide additional support and protection.
  • Applying Dressings After the graft is secured, a layered dressing is applied. This dressing typically includes a bulky layer of gauze to absorb any exudate, a compression layer to minimize swelling, and an anti-shear layer to protect the graft from friction and movement.

3. Post-Procedure

Post-procedure care following the application of an acellular dermal allograft is crucial for ensuring proper healing and minimizing complications. Patients are typically advised to keep the dressing intact and dry for a specified period, as determined by the healthcare provider. Regular monitoring of the graft site is essential to check for signs of infection, such as increased redness, swelling, or discharge. Patients may also be instructed on how to manage pain and discomfort, which can include the use of prescribed analgesics. Follow-up appointments are necessary to assess the healing process and to determine if any additional interventions are required. It is important to avoid any activities that could stress the graft site during the initial healing phase to promote optimal integration of the graft with the surrounding tissue.

Short Descr APLY ACELL GRFT F/N/HF/G ADD
Medium Descr ACLR DRM ALGRFT F/S/N/H/F/G/M/D GT EA 100 CM/EA
Long Descr ACLR DRM ALGRFT F/S/N/H/F/G/M/D GT EA 100 CM/EA
Status Code Active Code
Global Days ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Discontinued Code
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.
CCS Clinical Classification 172 - Skin graft
Date
Action
Notes
2012-01-01 Deleted Code deleted, see 15275-15278
2007-01-01 Changed Code description changed.
2006-01-01 Added Code added.
Code
Description
Code
Description
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