Coding Ahead
CasePilot
Medical Coding Assistant
Case2Code
Search and Code Lookup Tool
RedactPHI
HIPAA-Compliant PHI Redaction
DetectICD10CM
ICD-10-CM Code Detection
Log in Register free account
1 code page views remaining. Guest accounts are limited to 1 page view. Register free account to get 5 more views.
Log in Register free account
Code deleted, see 15271-15274

Official Description

Xenograft, skin (dermal), for temporary wound closure, trunk, arms, legs; first 100 sq cm or less, or 1% of body area of infants and children

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

A dermal xenograft, specifically identified by CPT® Code 15400, is a medical procedure involving the application of skin tissue obtained from a different species, commonly porcine (pig), to facilitate temporary wound closure. This procedure is typically performed on the trunk, arms, or legs of patients. The xenograft serves as a biological dressing, providing a protective layer over the wound until it is eventually rejected by the patient's immune system. The skin graft is processed through methods such as glycerol treatment and either freezing with liquid nitrogen or freeze-drying, also known as lyophilization, to preserve its viability. When ready for application, the xenograft is either thawed or rehydrated, depending on its preservation method, and is then carefully placed onto a prepared wound bed. The graft is secured in position using sutures to ensure it remains in place during the healing process. This code is applicable for the first 100 square centimeters of skin grafting in adults or for 1% of the total body surface area (TBSA) in infants and children. For any additional coverage beyond these parameters, CPT® Code 15401 should be utilized.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure involving the application of a dermal xenograft is indicated for the temporary closure of wounds located on the trunk, arms, or legs. This procedure is particularly relevant in cases where there is a need for a biological dressing to protect the wound and promote healing until the patient's own tissue can adequately cover the area. The use of xenografts is often considered in situations where traditional wound closure methods may not be suitable or effective.

  • Temporary Wound Closure The primary indication for the use of a dermal xenograft is to provide temporary closure for wounds that require protection and support during the healing process.
  • Wounds on Trunk, Arms, or Legs This procedure is specifically indicated for wounds located on the trunk, arms, or legs of patients.

2. Procedure

The procedure for applying a dermal xenograft involves several critical steps to ensure proper placement and effectiveness of the graft. Initially, the wound bed must be prepared, which may include cleaning the area and removing any necrotic tissue to create an optimal environment for graft application.

  • Step 1: Wound Bed Preparation The first step involves thoroughly cleaning the wound area to remove any debris or dead tissue. This preparation is essential to promote adherence of the xenograft and to minimize the risk of infection.
  • Step 2: Graft Preparation Once the wound bed is prepared, the xenograft is retrieved. If the graft has been frozen using liquid nitrogen, it is carefully thawed to restore its pliability. If it has been freeze-dried, it is rehydrated to ensure it is suitable for application.
  • Step 3: Application of the Graft The prepared xenograft is then placed onto the wound bed. It is crucial that the graft is positioned correctly to cover the entire wound area adequately.
  • Step 4: Securing the Graft After placement, the xenograft is secured in position using sutures. This step is vital to ensure that the graft remains in place and provides the necessary protection to the wound during the healing process.

3. Post-Procedure

After the application of the dermal xenograft, post-procedure care is essential to ensure optimal healing and minimize complications. Patients should be monitored for signs of infection or graft rejection. The area should be kept clean and dry, and any dressings should be changed as directed by the healthcare provider. Follow-up appointments may be necessary to assess the healing process and determine if additional interventions are required. It is important to educate patients on the signs of complications and the importance of adhering to post-procedure care instructions to promote successful outcomes.

Short Descr APPLY SKIN XENOGRAFT T/A/L
Medium Descr XENOGRAFT TEMP CLOSURE TRUNK/ARM/LEG 1ST 100CM
Long Descr Xenograft, skin (dermal), for temporary wound closure, trunk, arms, legs; first 100 sq cm or less, or 1% of body area of infants and children
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Discontinued Code
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.
CCS Clinical Classification 172 - Skin graft
Date
Action
Notes
2012-01-01 Deleted Code deleted, see 15271-15274
2011-01-01 Changed Short description changed.
2007-01-01 Changed Code description changed.
2006-01-01 Changed Code description changed.
Pre-1990 Added Code added.
Code
Description
Code
Description
CasePilot

Get instant expert-level medical coding assistance.

Ask about:
CPT Codes Guidelines Modifiers Crosswalks NCCI Edits Compliance Medicare Coverage
Example: "What is CPT code 99213?" or "Guidelines for E/M services"