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Official Description

Esophagogastroduodenoscopy, flexible, transoral; with endoscopic ultrasound examination limited to the esophagus, stomach or duodenum, and adjacent structures

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

An esophagogastroduodenoscopy (EGD) is a specialized upper gastrointestinal (UGI) endoscopic examination that allows for the visualization and assessment of the esophagus, stomach, and duodenum, as well as adjacent structures. This procedure is performed using a flexible fiberoptic endoscope, which is a thin, flexible tube equipped with a light and camera. The procedure begins with the administration of an anesthetic spray to numb the mouth and throat, facilitating the insertion of the endoscope. A hollow mouthpiece is placed in the patient's mouth to keep it open during the examination. As the patient swallows, the endoscope is carefully advanced through the esophagus, allowing for direct visualization of the esophageal lining and any potential abnormalities. During the procedure, an endoscopic ultrasound (EUS) is utilized to provide a detailed examination of the esophageal wall, which is visualized as a five-layer structure. The first two layers represent the mucosa, the third layer is the submucosa, the fourth layer is the muscularis propria, and the fifth layer is the serosa or adventitia. This detailed imaging capability of EUS enhances the diagnostic accuracy of the procedure. Following the examination of the esophagus, the endoscope is advanced into the stomach, where air is insufflated to expand the stomach for better visualization. The various regions of the stomach, including the cardia, fundus, greater and lesser curvature, and antrum, are inspected for abnormalities. The endoscope is then passed through the pylorus into the duodenum and/or jejunum, where the mucosal surfaces are again examined for any irregularities. After the thorough inspection, the endoscope is withdrawn, allowing for a final assessment of the mucosal surfaces for ulcerations, varices, bleeding sites, lesions, strictures, or other abnormalities. The procedure coded as 43237 encompasses the complete EGD of the upper gastrointestinal tract in conjunction with the EUS examination. If additional procedures such as transendoscopic ultrasound-guided fine needle aspiration or biopsy are performed, the code 43238 should be utilized.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The esophagogastroduodenoscopy (EGD) with endoscopic ultrasound examination is indicated for various clinical scenarios, including but not limited to the following:

  • Evaluation of Symptoms: Patients presenting with symptoms such as dysphagia (difficulty swallowing), odynophagia (painful swallowing), or unexplained weight loss may require this procedure for diagnostic purposes.
  • Investigation of Abnormal Imaging: Abnormal findings on imaging studies, such as CT scans or X-rays, may necessitate further evaluation of the esophagus, stomach, or duodenum.
  • Assessment of Gastrointestinal Disorders: Conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, or suspected malignancies can be assessed through this procedure.
  • Biopsy of Lesions: The procedure allows for the collection of tissue samples from suspicious lesions or masses found during the examination.

2. Procedure

The procedure involves several key steps that ensure a comprehensive examination of the upper gastrointestinal tract:

  • Preparation and Anesthesia: The patient is prepared for the procedure, and an anesthetic spray is applied to the mouth and throat to minimize discomfort during the insertion of the endoscope.
  • Insertion of the Endoscope: A hollow mouthpiece is placed in the patient's mouth to keep it open. The flexible fiberoptic endoscope is then inserted and advanced as the patient swallows, allowing for smooth passage through the esophagus.
  • Visualization of the Esophagus: Once the endoscope is beyond the cricopharyngeal region, it is guided using direct visualization. The esophagus is thoroughly inspected for any abnormalities, such as lesions or strictures.
  • Endoscopic Ultrasound Examination: An endoscopic ultrasound is advanced to provide detailed imaging of the esophageal wall, which is visualized as a five-layer structure, enhancing the diagnostic capabilities of the procedure.
  • Inspection of the Stomach: The endoscope is then advanced into the stomach, which is insufflated with air to improve visibility. The cardia, fundus, greater and lesser curvature, and antrum are inspected for abnormalities.
  • Advancement into the Duodenum: The tip of the endoscope is advanced through the pylorus into the duodenum and/or jejunum, where the mucosal surfaces are inspected for any irregularities.
  • Final Inspection: After the thorough examination, the endoscope is withdrawn, and the mucosal surfaces are again inspected for ulcerations, varices, bleeding sites, lesions, strictures, or other abnormalities.

3. Post-Procedure

Post-procedure care involves monitoring the patient for any immediate complications, such as bleeding or perforation. Patients are typically advised to rest until the effects of the anesthetic wear off. It is common for patients to experience a sore throat or mild discomfort following the procedure, which usually resolves quickly. Instructions regarding diet and activity levels may be provided, and follow-up appointments may be scheduled to discuss biopsy results or further management based on the findings of the EGD and EUS examination.

Short Descr ENDOSCOPIC US EXAM ESOPH
Medium Descr ESOPHAGOGASTRODUODENOSCOPY US SCOPE W/ADJ STRXRS
Long Descr Esophagogastroduodenoscopy, flexible, transoral; with endoscopic ultrasound examination limited to the esophagus, stomach or duodenum, and adjacent structures
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 3 - Special payment adjustment rules for multiple endoscopic procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Endoscopic Base Code 43235  Esophagogastroduodenoscopy, flexible, transoral; diagnostic, including collection of specimen(s) by brushing or washing, when performed (separate procedure)
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P8B - Endoscopy - upper gastrointestinal
MUE 1
CCS Clinical Classification 70 - Upper gastrointestinal endoscopy, biopsy
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
GC This service has been performed in part by a resident under the direction of a teaching physician
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
SG Ambulatory surgical center (asc) facility service
CR Catastrophe/disaster related
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
74 Discontinued out-patient hospital/ambulatory surgery center (asc) procedure after administration of anesthesia: due to extenuating circumstances or those that threaten the well being of the patient, the physician may terminate a surgical or diagnostic procedure after the administration of anesthesia (local, regional block(s), general) or after the procedure was started (incision made, intubation started, scope inserted, etc). under these circumstances, the procedure started but terminated can be reported by its usual procedure number and the addition of modifier 74. note: the elective cancellation of a service prior to the administration of anesthesia and/or surgical preparation of the patient should not be reported. for physician reporting of a discontinued procedure, see modifier 53.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AG Primary physician
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CG Policy criteria applied
GA Waiver of liability statement issued as required by payer policy, individual case
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
GZ Item or service expected to be denied as not reasonable and necessary
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
PT Colorectal cancer screening test; converted to diagnostic test or other procedure
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
RT Right side (used to identify procedures performed on the right side of the body)
X2 Continuous/focused services: for reporting services by clinicians whose expertise is needed for the ongoing management of a chronic disease or a condition that needs to be managed and followed with no planned endpoint to the relationship; reporting clinician service examples include but are not limited to: a rheumatologist taking care of the patient's rheumatoid arthritis longitudinally but not providing general primary care services
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2017-01-01 Changed Moderate (Conscious) Sedation flag removed. See new Moderate Sedation category.
2014-01-01 Changed Description Changed
2011-01-01 Changed Short description changed.
2004-01-01 Added First appearance in code book in 2004.
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