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Official Description

Injection(s), anesthetic agent(s) and/or steroid; nerves innervating the sacroiliac joint, with image guidance (ie, fluoroscopy or computed tomography)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 64451 refers to the procedure of injecting anesthetic agents and/or steroids into the nerves that innervate the sacroiliac joint, utilizing image guidance techniques such as fluoroscopy or computed tomography. This procedure, commonly known as a sacroiliac (SI) joint nerve block, is primarily indicated for the treatment or diagnosis of low back pain and/or sciatic pain that arises from dysfunction of the SI joint. The sacroiliac joints are located where the sacrum meets the hip bones on either side of the spine, playing a crucial role in the stability and movement of the pelvis. During the procedure, the skin at the injection site is meticulously prepared to minimize the risk of infection. A needle is then carefully advanced into the SI joint, often under the guidance of fluoroscopy to ensure precise placement. Prior to the injection of the nerve blocking agent, a contrast medium may be introduced to confirm the correct positioning of the needle and to visualize the distribution of the medication. For diagnostic purposes, a local anesthetic, such as lidocaine, may be administered first, allowing the patient to assess pain relief. If significant pain relief, typically between 75-80%, is achieved, this can help establish a preliminary diagnosis. Subsequently, a different anesthetic agent, like bupivacaine, may be injected to further evaluate the persistence of pain relief, thereby confirming the diagnosis of SI joint dysfunction. In therapeutic scenarios, the injection may consist of an anesthetic agent combined with an anti-inflammatory corticosteroid, administered in a similar manner to alleviate pain and inflammation associated with the condition.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure described by CPT® Code 64451 is indicated for the following conditions:

  • Low Back Pain The injection is performed to diagnose or treat low back pain that may be originating from the sacroiliac joint.
  • Sciatic Pain This procedure is also indicated for patients experiencing sciatic pain due to dysfunction of the sacroiliac joint.
  • Sacroiliac Joint Dysfunction The primary indication for this procedure is to address issues related to sacroiliac joint dysfunction, which can lead to significant discomfort and mobility issues.

2. Procedure

The procedure involves several key steps to ensure accurate delivery of the anesthetic agent and/or steroid:

  • Preparation of the Injection Site The skin at the site of injection is thoroughly cleaned and prepped to reduce the risk of infection. This step is crucial for maintaining a sterile environment during the procedure.
  • Needle Advancement A needle is carefully advanced into the sacroiliac joint. This is typically done under image guidance, such as fluoroscopy, to ensure precise placement of the needle within the joint space.
  • Contrast Injection Before administering the anesthetic agent, a contrast medium may be injected to confirm the accurate positioning of the needle. This allows the physician to visualize the spread of the medication and ensure it reaches the targeted area.
  • Injection of Nerve Blocking Agent Once the needle placement is confirmed, the nerve blocking agent is injected into the sacroiliac joint. This may involve the use of a local anesthetic, such as lidocaine, for diagnostic purposes, followed by a different anesthetic agent, like bupivacaine, to assess the duration of pain relief.
  • Assessment of Pain Relief For diagnostic blocks, the patient is asked to evaluate their pain levels after the initial injection. If 75-80% pain relief is achieved, this can help in making a tentative diagnosis of SI joint dysfunction.
  • Therapeutic Injection In cases where the procedure is performed for therapeutic pain relief, an anesthetic agent may be combined with an anti-inflammatory corticosteroid and injected in the same manner to provide longer-lasting relief from pain and inflammation.

3. Post-Procedure

After the procedure, patients are typically monitored for any immediate adverse reactions to the injection. It is common for patients to experience some soreness at the injection site, which may resolve within a few days. Patients may be advised to rest and avoid strenuous activities for a short period following the injection. The physician may schedule a follow-up appointment to assess the effectiveness of the procedure and determine the next steps in the management of the patient's pain. Additionally, patients should be informed about potential side effects of the anesthetic and corticosteroid, as well as signs of complications that would require immediate medical attention.

Short Descr NJX AA&/STRD NRV NRVTG SI JT
Medium Descr INJECTION AA&/STRD NERVES NRVTG SI JOINT W/IMG
Long Descr Injection(s), anesthetic agent(s) and/or steroid; nerves innervating the sacroiliac joint, with image guidance (ie, fluoroscopy or computed tomography)
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 1 - 150% payment adjustment for bilateral procedures applies.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Multiple Reduction Applies
ASC Payment Indicator Non office-based surgical procedure added in CY 2008 or later; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) none
MUE 1
50 Bilateral procedure: unless otherwise identified in the listings, bilateral procedures that are performed at the same session, should be identified by adding modifier 50 to the appropriate 5 digit code. note: this modifier should not be appended to designated "add-on" codes (see appendix d).
RT Right side (used to identify procedures performed on the right side of the body)
LT Left side (used to identify procedures performed on the left side of the body)
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
KX Requirements specified in the medical policy have been met
GA Waiver of liability statement issued as required by payer policy, individual case
SG Ambulatory surgical center (asc) facility service
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
73 Discontinued out-patient hospital/ambulatory surgery center (asc) procedure prior to the administration of anesthesia: due to extenuating circumstances or those that threaten the well being of the patient, the physician may cancel a surgical or diagnostic procedure subsequent to the patient's surgical preparation (including sedation when provided, and being taken to the room where the procedure is to be performed), but prior to the administration of anesthesia (local, regional block(s) or general). under these circumstances, the intended service that is prepared for but cancelled can be reported by its usual procedure number and the addition of modifier 73. note: the elective cancellation of a service prior to the administration of anesthesia and/or surgical preparation of the patient should not be reported. for physician reporting of a discontinued procedure, see modifier 53.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CR Catastrophe/disaster related
GC This service has been performed in part by a resident under the direction of a teaching physician
GW Service not related to the hospice patient's terminal condition
GZ Item or service expected to be denied as not reasonable and necessary
PT Colorectal cancer screening test; converted to diagnostic test or other procedure
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
X2 Continuous/focused services: for reporting services by clinicians whose expertise is needed for the ongoing management of a chronic disease or a condition that needs to be managed and followed with no planned endpoint to the relationship; reporting clinician service examples include but are not limited to: a rheumatologist taking care of the patient's rheumatoid arthritis longitudinally but not providing general primary care services
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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2020-01-01 Added Code added.
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