2 code page views remaining today. Guest accounts are limited to 2 daily page views. Register free account to get more views.
Log in Register free account

Official Description

Injection(s), anesthetic agent(s) and/or steroid; transforaminal epidural, with imaging guidance (fluoroscopy or CT), cervical or thoracic, each additional level (List separately in addition to code for primary procedure)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

A transforaminal epidural injection is a medical procedure designed to deliver anesthetic agents and/or steroids directly around a specific nerve root. This procedure is particularly useful for patients experiencing pain or discomfort that may be related to nerve root irritation or inflammation. The foramina are small openings located between the vertebrae through which nerve roots exit the spinal canal. During the procedure, the skin over the affected cervical or thoracic vertebra is thoroughly cleansed and prepared to minimize the risk of infection. Utilizing advanced imaging techniques such as computed tomography (CT) or fluoroscopy, a healthcare provider carefully advances a needle through the skin and into the foramen, ensuring precise placement. To confirm the correct positioning of the needle, a small amount of radiopaque contrast material may be injected, which enhances the visibility of the needle on imaging. Once the needle is correctly positioned, the anesthetic and/or steroid is injected around the nerve root, providing targeted relief from pain and inflammation. It is important to note that CPT® Code 64480 is specifically used for each additional level of injection performed, following the primary procedure coded with 64479, which is designated for a single cervical or thoracic level injection.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The transforaminal epidural injection procedure is indicated for various conditions that may cause pain or discomfort due to nerve root involvement. These indications include:

  • Radiculopathy - A condition characterized by pain that radiates along the path of a nerve due to compression or irritation, often resulting from herniated discs or spinal stenosis.
  • Herniated Disc - The displacement of disc material that can press on nerve roots, leading to pain, numbness, or weakness in the extremities.
  • Spinal Stenosis - A narrowing of the spinal canal that can compress nerve roots and cause pain, particularly in the neck or back.
  • Post-surgical Pain - Persistent pain following spinal surgery that may benefit from targeted injection therapy.

2. Procedure

The transforaminal epidural injection procedure involves several key steps to ensure accurate delivery of the anesthetic and/or steroid. These steps include:

  • Preparation - The patient is positioned appropriately, and the skin over the targeted cervical or thoracic vertebra is cleansed with an antiseptic solution to reduce the risk of infection.
  • Imaging Guidance - The provider utilizes fluoroscopy or CT imaging to visualize the anatomy and guide the needle placement accurately. This imaging is crucial for ensuring that the needle is directed towards the foramen where the nerve root exits.
  • Needle Insertion - A thin needle is carefully advanced through the skin and into the foramen under imaging guidance. The provider monitors the needle's position in real-time to ensure it reaches the correct location.
  • Contrast Injection - A small amount of radiopaque contrast material may be injected to confirm the proper placement of the needle. This step enhances the visibility of the needle on imaging and ensures that it is correctly positioned around the nerve root.
  • Medication Injection - Once the needle is confirmed to be in the correct position, the anesthetic agent and/or steroid is injected around the nerve root. This targeted delivery aims to alleviate pain and reduce inflammation effectively.

3. Post-Procedure

After the transforaminal epidural injection, patients are typically monitored for a short period to assess for any immediate adverse reactions. It is common for patients to experience some relief from pain shortly after the procedure, although the full effect may take several days to manifest. Patients are usually advised to avoid strenuous activities for a short period following the injection to allow for optimal recovery. Additionally, they may be instructed to follow up with their healthcare provider to evaluate the effectiveness of the injection and discuss any further treatment options if necessary.

Short Descr NJX AA&/STRD TFRM EPI C/T EA
Medium Descr NJX AA&/STRD TFRML EPI CERVICAL/THORACIC EA ADDL
Long Descr Injection(s), anesthetic agent(s) and/or steroid; transforaminal epidural, with imaging guidance (fluoroscopy or CT), cervical or thoracic, each additional level (List separately in addition to code for primary procedure)
Status Code Active Code
Global Days ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 1 - 150% payment adjustment for bilateral procedures applies.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
ASC Payment Indicator Packaged service/item; no separate payment made.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P6B - Minor procedures - musculoskeletal
MUE 4
CCS Clinical Classification 5 - Insertion of catheter or spinal stimulator and injection into spinal canal

This is an add-on code that must be used in conjunction with one of these primary codes.

64479 MPFS Status: Active Code APC T ASC A2 CPT Assistant Article Injection(s), anesthetic agent(s) and/or steroid; transforaminal epidural, with imaging guidance (fluoroscopy or CT), cervical or thoracic, single level
RT Right side (used to identify procedures performed on the right side of the body)
LT Left side (used to identify procedures performed on the left side of the body)
50 Bilateral procedure: unless otherwise identified in the listings, bilateral procedures that are performed at the same session, should be identified by adding modifier 50 to the appropriate 5 digit code. note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
KX Requirements specified in the medical policy have been met
SG Ambulatory surgical center (asc) facility service
GA Waiver of liability statement issued as required by payer policy, individual case
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
74 Discontinued out-patient hospital/ambulatory surgery center (asc) procedure after administration of anesthesia: due to extenuating circumstances or those that threaten the well being of the patient, the physician may terminate a surgical or diagnostic procedure after the administration of anesthesia (local, regional block(s), general) or after the procedure was started (incision made, intubation started, scope inserted, etc). under these circumstances, the procedure started but terminated can be reported by its usual procedure number and the addition of modifier 74. note: the elective cancellation of a service prior to the administration of anesthesia and/or surgical preparation of the patient should not be reported. for physician reporting of a discontinued procedure, see modifier 53.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
AG Primary physician
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
GC This service has been performed in part by a resident under the direction of a teaching physician
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
GZ Item or service expected to be denied as not reasonable and necessary
MG The order for this service does not have applicable appropriate use criteria in the qualified clinical decision support mechanism consulted by the ordering professional
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
X2 Continuous/focused services: for reporting services by clinicians whose expertise is needed for the ongoing management of a chronic disease or a condition that needs to be managed and followed with no planned endpoint to the relationship; reporting clinician service examples include but are not limited to: a rheumatologist taking care of the patient's rheumatoid arthritis longitudinally but not providing general primary care services
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2021-01-01 Changed Code changed.
2013-01-01 Changed Description Changed
2011-01-01 Changed Long description revised. Medium description changed. Guideline information changed.
2000-01-01 Added First appearance in code book in 2000.
Code
Description
Code
Description
Code
Description
Code
Description
Code
Description