CPT® Code 90758

Official Description

Zaire ebolavirus vaccine, live, for intramuscular use

Common Language Description

The CPT® Code 90758 refers to the Zaire ebolavirus vaccine, which is a live vaccine administered via intramuscular injection. Vaccines, unlike immune globulins that offer short-term, passive immunity, provide active and long-term immunity. This is achieved by exposing the recipient's immune system to altered forms of specific viruses or bacteria, prompting the immune system to produce its own antibodies against the microorganism. The immune system retains a memory of how to produce these antibodies, allowing for a quicker and more effective response upon subsequent exposures to the same antigen. The Zaire ebolavirus vaccine specifically contains an attenuated, or weakened, form of the live virus, which is designed to stimulate an immune response without causing the actual disease. This vaccine is crucial for protecting against the rare but serious Ebola virus disease (EBV), primarily used as a pre-exposure prophylactic measure for individuals aged 18 and older who are at occupational risk of exposure. This includes laboratory personnel and healthcare workers operating in designated facilities. The Ebola virus is known to exist in certain animal populations across various sub-Saharan African countries and can be transmitted to humans through contact with infected animals, subsequently spreading from person to person.

1. Indications

The Zaire ebolavirus vaccine is indicated for individuals who are at occupational risk of exposure to the Ebola virus. This includes specific groups such as:

Laboratory Staff Individuals working in laboratories that handle the Ebola virus or related pathogens.
Healthcare Workers Professionals providing care in designated facilities where Ebola virus disease may be present.
Individuals Aged 18 and Older The vaccine is specifically recommended for adults who are at risk due to their occupation.

2. Procedure

The administration of the Zaire ebolavirus vaccine involves several key procedural steps:

Preparation of the Vaccine The vaccine must be prepared according to the manufacturer's guidelines, ensuring that it is stored at the appropriate temperature and is not expired. The vial should be inspected for any particulate matter or discoloration before use.
Patient Assessment Prior to vaccination, a thorough assessment of the patient’s medical history should be conducted to identify any contraindications or previous allergic reactions to vaccines. The patient should be informed about the vaccine, its purpose, and potential side effects.
Administration of the Vaccine The vaccine is administered via intramuscular injection, typically in the deltoid muscle of the upper arm. The injection site should be cleaned with an antiseptic wipe to minimize the risk of infection. The healthcare provider should use a sterile needle and syringe to draw up the vaccine and administer it.
Post-Administration Monitoring After the vaccine is administered, the patient should be monitored for a short period to observe for any immediate adverse reactions. This is typically done for 15-30 minutes in a clinical setting.

3. Post-Procedure

Following the administration of the Zaire ebolavirus vaccine, patients may experience mild side effects such as soreness at the injection site, fever, or fatigue. It is important to provide patients with information on managing these symptoms and to advise them to seek medical attention if they experience severe or unusual reactions. Patients should also be informed about the importance of follow-up vaccinations if required and the need for continued monitoring for any signs of Ebola virus exposure, especially if they work in high-risk environments.

Short Descr	ZAIRE EBOLAVIRUS VAC LIVE IM
Medium Descr	ZAIRE EBOLAVIRUS VACCINE LIVE FOR IM USE
Long Descr	Zaire ebolavirus vaccine, live, for intramuscular use
Status Code	Non-Covered Service
Global Days	XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC)	9 - Not Applicable
Multiple Procedures (51)	9 - Concept does not apply.
Bilateral Surgery (50)	9 - Concept does not apply.
Physician Supervisions	09 - Concept does not apply.
Assistant Surgeon (80, 82)	9 - Concept does not apply.
Co-Surgeons (62)	9 - Concept does not apply.
Team Surgery (66)	9 - Concept does not apply.
Diagnostic Imaging Family	99 - Concept Does Not Apply
APC Status Indicator	Non-Covered Service, not paid under OPPS
Type of Service (TOS)	1 - Medical Care
Berenson-Eggers TOS (BETOS)	none
MUE	1