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Official Description

Coagulation/fibrinolysis assay, whole blood (eg, viscoelastic clot assessment), including use of any pharmacologic additive(s), as indicated, including interpretation and written report, per day

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 85396 refers to a coagulation/fibrinolysis assay performed on whole blood, which is a laboratory test designed to evaluate the body's ability to form and dissolve blood clots. This assay utilizes pharmacologic additives as necessary to enhance the assessment process. The primary purpose of this test is to provide a comprehensive evaluation of a patient's risk for hemorrhage or thrombosis by measuring various components involved in the clotting cascade. Key elements assessed include the rate of clot formation, the strength of the clot, and its stability, which are determined through the analysis of fibrin formation, platelet function, and fibrinolytic activity. The whole blood assay is particularly valuable in clinical scenarios involving acute bleeding or major trauma, as it offers a broad perspective on hemostatic imbalances that may be present. This information is crucial for guiding appropriate transfusion support and other therapeutic interventions. The test is conducted by obtaining a blood sample, which can be collected through a separately reportable venipuncture, arterial draw, or central line draw. The analysis is performed using thromboelastogram (TEG) techniques, specifically with the addition of plain kaolin and heparinase to the whole blood sample. Following the assay, a written report is generated by a pathologist or another qualified professional, detailing patient-specific diagnostic information, treatment strategies, and recommendations for future testing options.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The coagulation/fibrinolysis assay (CPT® Code 85396) is indicated for use in various clinical situations where assessment of hemostatic function is necessary. The following conditions may warrant the performance of this assay:

  • Acute Bleeding: The assay is utilized to evaluate patients experiencing significant bleeding episodes, allowing for timely intervention and management.
  • Major Trauma: In cases of major trauma, this test helps assess the hemostatic status of the patient, guiding transfusion and treatment decisions.
  • Thrombotic Risk Assessment: The assay aids in identifying patients at risk for thrombotic events, facilitating preventive measures and treatment strategies.

2. Procedure

The procedure for conducting the coagulation/fibrinolysis assay involves several key steps that ensure accurate assessment of the patient's hemostatic function. The following outlines the procedural steps:

  • Step 1: Blood Sample Collection - A blood sample is obtained from the patient through a venipuncture, arterial draw, or central line draw. This step is crucial as it provides the whole blood necessary for the assay. The method of collection should be appropriate for the clinical scenario and the patient's condition.
  • Step 2: Preparation of the Sample - Once the blood sample is collected, it is prepared for testing. This involves the addition of specific pharmacologic additives, such as plain kaolin and heparinase, which are used to enhance the assessment of the clotting process.
  • Step 3: Conducting the Assay - The prepared whole blood sample is then subjected to the thromboelastogram (TEG) analysis. This technique allows for the evaluation of various parameters related to clot formation, strength, and stability, providing a comprehensive view of the patient's hemostatic function.
  • Step 4: Interpretation of Results - After the assay is completed, the results are interpreted by a qualified professional, such as a pathologist. This interpretation includes an analysis of the data obtained from the TEG, focusing on the patient's coagulation status and any potential imbalances.
  • Step 5: Reporting - A written report is generated, detailing the findings of the assay. This report includes patient-specific diagnostic information, treatment strategies, and recommendations for any future testing that may be necessary.

3. Post-Procedure

Post-procedure care following the coagulation/fibrinolysis assay primarily involves monitoring the patient for any adverse reactions related to the blood draw and ensuring that the results are communicated effectively to the healthcare team. The written report generated from the assay should be reviewed promptly to inform clinical decision-making regarding treatment options and potential follow-up testing. Additionally, healthcare providers should consider the implications of the assay results on the patient's ongoing management, particularly in cases of acute bleeding or thrombotic risk.

Short Descr CLOTTING ASSAY WHOLE BLOOD
Medium Descr COAGJ/FBRNLYS ASSAY WHOLE BLOOD ADDITIVE PER DAY
Long Descr Coagulation/fibrinolysis assay, whole blood (eg, viscoelastic clot assessment), including use of any pharmacologic additive(s), as indicated, including interpretation and written report, per day
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1G - Lab tests - other (Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
25 Significant, separately identifiable evaluation and management service by the same physician or other qualified health care professional on the same day of the procedure or other service: it may be necessary to indicate that on the day a procedure or service identified by a cpt code was performed, the patient's condition required a significant, separately identifiable e/m service above and beyond the other service provided or beyond the usual preoperative and postoperative care associated with the procedure that was performed. a significant, separately identifiable e/m service is defined or substantiated by documentation that satisfies the relevant criteria for the respective e/m service to be reported (see evaluation and management services guidelines for instructions on determining level of e/m service). the e/m service may be prompted by the symptom or condition for which the procedure and/or service was provided. as such, different diagnoses are not required for reporting of the e/m services on the same date. this circumstance may be reported by adding modifier 25 to the appropriate level of e/m service. note: this modifier is not used to report an e/m service that resulted in a decision to perform surgery. see modifier 57 for significant, separately identifiable non-e/m services, see modifier 59.
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
GC This service has been performed in part by a resident under the direction of a teaching physician
GW Service not related to the hospice patient's terminal condition
Date
Action
Notes
2011-01-01 Changed Short description changed.
2004-01-01 Added First appearance in code book in 2004.
1986-12-31 Deleted Code deleted.
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Description
Code
Description
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