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The CPT® Code 85576 refers to a laboratory test that evaluates platelet aggregation, which is the process by which platelets clump together to form a blood clot. This test is conducted in vitro, meaning it takes place outside of a living organism, typically in a laboratory setting. During the procedure, various known platelet activators are introduced to whole blood samples to assess how well the platelets respond. These activators can include substances such as adenosine diphosphate (ADP), arachidonic acid, thrombin, epinephrine, and ristocetin. The response of the platelets to these agents is monitored to determine their aggregation ability. This test serves multiple purposes in clinical practice. It may be utilized to screen patients who are at risk for bleeding complications prior to surgical procedures, allowing healthcare providers to make informed decisions regarding patient safety. Additionally, it can be used to monitor platelet function during surgery, ensuring that the patient's hemostatic capabilities are adequate. The test is also valuable in detecting aspirin resistance, which can occur in patients who are on anti-platelet therapy but continue to experience thrombotic events. Furthermore, it aids in diagnosing and evaluating conditions associated with excessive bruising or bleeding disorders. In particular, ristocetin activator testing can assist in subtyping von Willebrand syndrome, a genetic bleeding disorder. The test requires a blood sample, which is obtained through a separately reportable venipuncture, and the whole blood is analyzed using methods such as aggregation, quantitative aggregation, or light transmission aggregometry.
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The CPT® Code 85576 is indicated for use in various clinical scenarios where platelet function assessment is necessary. The following conditions and situations warrant the performance of this test:
The procedure for CPT® Code 85576 involves several key steps to ensure accurate measurement of platelet aggregation. The following outlines the procedural steps:
After the completion of the platelet aggregation test, the patient may be monitored for any immediate complications related to the venipuncture, such as bleeding or bruising at the site. The results of the test will be compiled and reported to the requesting physician, who will use the information to make informed clinical decisions regarding the patient's care. Depending on the findings, further testing or interventions may be recommended, especially if abnormalities in platelet function are detected. It is important for healthcare providers to discuss the results with the patient and outline any necessary follow-up actions or treatments based on the test outcomes.
| Short Descr | BLOOD PLATELET AGGREGATION | Medium Descr | PLATELET AGGREGATION IN VITRO EACH AGENT | Long Descr | Platelet, aggregation (in vitro), each agent | Status Code | Active Code | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 6 - Laboratory Physician Interpretation Code | Multiple Procedures (51) | 0 - No payment adjustment rules for multiple procedures apply. | Bilateral Surgery (50) | 0 - 150% payment adjustment for bilateral procedures does NOT apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 0 - Payment restriction for assistants at surgery applies to this procedure... | Co-Surgeons (62) | 0 - Co-surgeons not permitted for this procedure. | Team Surgery (66) | 0 - Team surgeons not permitted for this procedure. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | Yes | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 7 | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
| 26 | Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number. | QW | Clia waived test | 90 | Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number. | 59 | Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25. | 91 | Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient. | XU | Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service | GW | Service not related to the hospice patient's terminal condition | XE | Separate encounter, a service that is distinct because it occurred during a separate encounter | 76 | Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service. | TC | Technical component; under certain circumstances, a charge may be made for the technical component alone; under those circumstances the technical component charge is identified by adding modifier 'tc' to the usual procedure number; technical component charges are institutional charges and not billed separately by physicians; however, portable x-ray suppliers only bill for technical component and should utilize modifier tc; the charge data from portable x-ray suppliers will then be used to build customary and prevailing profiles | GA | Waiver of liability statement issued as required by payer policy, individual case | GC | This service has been performed in part by a resident under the direction of a teaching physician | GV | Attending physician not employed or paid under arrangement by the patient's hospice provider | Q1 | Routine clinical service provided in a clinical research study that is in an approved clinical research study | X5 | Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician | XP | Separate practitioner, a service that is distinct because it was performed by a different practitioner | XS | Separate structure, a service that is distinct because it was performed on a separate organ/structure |
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Action
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Notes
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| 2003-01-01 | Changed | Code description changed. |
| 1992-12-31 | Deleted | Code deleted. |
| Pre-1990 | Added | Code added. |
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