Coding Ahead
CasePilot
Medical Coding Assistant
Case2Code
Search and Code Lookup Tool
RedactPHI
HIPAA-Compliant PHI Redaction
DetectICD10CM
ICD-10-CM Code Detection
Log in Register free account
1 code page views remaining. Guest accounts are limited to 1 page view. Register free account to get 5 more views.
Log in Register free account

Official Description

Influenza virus vaccine (IIV), split virus, preservative free, enhanced immunogenicity via increased antigen content, for intramuscular use

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 90662 refers to a specific formulation of the influenza virus vaccine, which is a split virus, preservative-free vaccine designed for intramuscular use. This vaccine is characterized by its enhanced immunogenicity, achieved through an increased antigen content. Unlike immune globulins that offer short-term, passive immunity, vaccines like this one provide active, long-term immunity. They do so by exposing the recipient's immune system to modified versions of the influenza virus, prompting the immune system to produce its own antibodies. This process enables the body to "remember" how to generate these antibodies upon subsequent exposure to the same virus. The preservative-free aspect of this vaccine indicates that it contains either no thimerosal or only trace amounts, which the FDA recognizes as preservative-free. The vaccine is produced using embryonated chicken eggs, where the virus is harvested, inactivated with formaldehyde, and then concentrated to enhance the antigen content. Following this, the virus undergoes chemical disruption to create a split virus, which is further purified. This particular formulation is especially beneficial for the elderly population, who may have a diminished immune response, making the enhanced immunogenicity crucial for effective vaccination. It is important to note that this code specifically reports the vaccine product itself and does not include the administration of the vaccine, which is billed separately.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The enhanced immunogenicity split-virus influenza vaccine (CPT® Code 90662) is indicated for use in specific populations, particularly where immune responsiveness may be compromised. The primary indications for administering this vaccine include:

  • Elderly Population - This vaccine is particularly recommended for older adults, as their immune systems may not respond as robustly to standard vaccines, making enhanced immunogenicity critical for effective protection against influenza.

2. Procedure

The procedure for administering the influenza virus vaccine (CPT® Code 90662) involves several key steps to ensure proper delivery and effectiveness of the vaccine. Each step is crucial for maintaining the integrity of the vaccine and ensuring patient safety.

  • Preparation of the Vaccine - The vaccine is prepared by ensuring that it is stored at the appropriate temperature and is not expired. The vial is inspected for any particulate matter or discoloration before use. If the vaccine is in a multi-dose vial, it is important to use aseptic technique to withdraw the correct dosage.
  • Patient Assessment - Prior to administration, the healthcare provider assesses the patient’s medical history, including any previous allergic reactions to vaccines, current medications, and overall health status to determine if the patient is a suitable candidate for the vaccine.
  • Administration of the Vaccine - The vaccine is administered via intramuscular injection, typically in the deltoid muscle of the upper arm. The injection site is cleaned with an alcohol swab to reduce the risk of infection. The needle is inserted at a 90-degree angle to ensure proper delivery into the muscle tissue.
  • Post-Administration Monitoring - After the vaccine is administered, the patient is monitored for a short period to observe for any immediate adverse reactions. This is particularly important for patients with a history of allergies or previous vaccine reactions.

3. Post-Procedure

Following the administration of the influenza virus vaccine (CPT® Code 90662), patients are typically advised to remain in the healthcare setting for a brief observation period, usually around 15 minutes, to monitor for any immediate side effects or allergic reactions. Common post-vaccination care includes advising the patient to apply a cool compress to the injection site if they experience soreness or swelling. Patients should also be informed about potential mild side effects, such as low-grade fever, fatigue, or muscle aches, which are generally self-limiting. It is important for patients to be educated on the signs of a severe allergic reaction, such as difficulty breathing or swelling of the face and throat, and to seek immediate medical attention if these occur. Additionally, patients should be encouraged to report any unusual or severe reactions to their healthcare provider. Follow-up appointments may be scheduled as necessary, especially for those requiring additional vaccinations or boosters.

Short Descr IIV NO PRSV INCREASED AG IM
Medium Descr IIV VACCINE PRESERV FREE INCREASED AG CONTENT IM
Long Descr Influenza virus vaccine (IIV), split virus, preservative free, enhanced immunogenicity via increased antigen content, for intramuscular use
Related Drugs FLUZONE HIGH DOSE NORTHERN HEMISPHERE
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Influenza, Pneumococcal Pneumonia, Hepatitis B, and Covid-19 Vaccines; Monoclonal Antibody Therapy Product
ASC Payment Indicator Influenza vaccine; pneumococcal vaccine.
Type of Service (TOS) V - Pneumococcal/Flu Vaccine
Berenson-Eggers TOS (BETOS) O1G - Immunizations/Vaccinations
MUE 1
CCS Clinical Classification 228 - Prophylactic vaccinations and inoculations
JZ Zero drug amount discarded/not administered to any patient
X1 Continuous/broad services: for reporting services by clinicians, who provide the principal care for a patient, with no planned endpoint of the relationship; services in this category represent comprehensive care, dealing with the entire scope of patient problems, either directly or in a care coordination role; reporting clinician service examples include, but are not limited to: primary care, and clinicians providing comprehensive care to patients in addition to specialty care
GW Service not related to the hospice patient's terminal condition
GA Waiver of liability statement issued as required by payer policy, individual case
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GC This service has been performed in part by a resident under the direction of a teaching physician
SL State supplied vaccine
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CR Catastrophe/disaster related
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
LT Left side (used to identify procedures performed on the left side of the body)
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
SA Nurse practitioner rendering service in collaboration with a physician
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
GZ Item or service expected to be denied as not reasonable and necessary
99 Multiple modifiers: under certain circumstances 2 or more modifiers may be necessary to completely delineate a service. in such situations modifier 99 should be added to the basic procedure, and other applicable modifiers may be listed as part of the description of the service.
SK Member of high risk population (use only with codes for immunization)
UC Medicaid level of care 12, as defined by each state
RT Right side (used to identify procedures performed on the right side of the body)
25 Significant, separately identifiable evaluation and management service by the same physician or other qualified health care professional on the same day of the procedure or other service: it may be necessary to indicate that on the day a procedure or service identified by a cpt code was performed, the patient's condition required a significant, separately identifiable e/m service above and beyond the other service provided or beyond the usual preoperative and postoperative care associated with the procedure that was performed. a significant, separately identifiable e/m service is defined or substantiated by documentation that satisfies the relevant criteria for the respective e/m service to be reported (see evaluation and management services guidelines for instructions on determining level of e/m service). the e/m service may be prompted by the symptom or condition for which the procedure and/or service was provided. as such, different diagnoses are not required for reporting of the e/m services on the same date. this circumstance may be reported by adding modifier 25 to the appropriate level of e/m service. note: this modifier is not used to report an e/m service that resulted in a decision to perform surgery. see modifier 57 for significant, separately identifiable non-e/m services, see modifier 59.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CG Policy criteria applied
GE This service has been performed by a resident without the presence of a teaching physician under the primary care exception
GT Via interactive audio and video telecommunication systems
HA Child/adolescent program
HX Funded by county/local agency
HZ Funded by criminal justice agency
JW Drug amount discarded/not administered to any patient
KO Single drug unit dose formulation
KP First drug of a multiple drug unit dose formulation
KX Requirements specified in the medical policy have been met
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
PN Non-excepted service provided at an off-campus, outpatient, provider-based department of a hospital
PO Excepted service provided at an off-campus, outpatient, provider-based department of a hospital
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q5 Service furnished under a reciprocal billing arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
TB Drug or biological acquired with 340b drug pricing program discount, reported for informational purposes
U6 Medicaid level of care 6, as defined by each state
UA Medicaid level of care 10, as defined by each state
UD Medicaid level of care 13, as defined by each state
X2 Continuous/focused services: for reporting services by clinicians whose expertise is needed for the ongoing management of a chronic disease or a condition that needs to be managed and followed with no planned endpoint to the relationship; reporting clinician service examples include but are not limited to: a rheumatologist taking care of the patient's rheumatoid arthritis longitudinally but not providing general primary care services
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
Date
Action
Notes
2018-01-01 Changed Medium Description revised.
2016-01-01 Changed First appearance of change in codebook.
2015-07-01 Changed Description Changed
2011-01-01 Changed FDA Approval Pending status changed.
2009-01-01 Changed -
2008-01-01 Added -
Code
Description
Code
Description
CasePilot

Get instant expert-level medical coding assistance.

Ask about:
CPT Codes Guidelines Modifiers Crosswalks NCCI Edits Compliance Medicare Coverage
Example: "What is CPT code 99213?" or "Guidelines for E/M services"